Effect of Ketamine on post-operative intraocular inflammation following cataract surgery

ISRCTN	ISRCTN84553798
DOI	https://doi.org/10.1186/ISRCTN84553798
Secondary identifying numbers	N0207129695

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Mr S B Kaye
Scientific

St Pauls Eye Unit
8Z Link
Royal Liverpool University Hospital
Prescot Street
Liverpool
L7 8XP
United Kingdom

Phone	+44 (0)151 706 2134
Email	Stephen.kaye@rlbuht.nhs.uk

Study design	Prospective, randomised, parallel group, double blind, clinical trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Treatment
Scientific title
Study objectives	Does ketamine reduce post-operative cystoid macula oedema in patients who undergo cataract surgery?
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Surgery: Cataract
Intervention	Group A receive ketamine under general anaesthetic Group B receive general anaesthetic without ketamine Group C receive local anaesthetic without ketamine
Intervention type	Drug
Pharmaceutical study type(s)
Phase	Not Specified
Drug / device / biological / vaccine name(s)	ketamine
Primary outcome measure	To define population for definitive randomised prospective trial on effects of ketamine on cystoid macula oedema in patients undergoing cataract surgery
Secondary outcome measures	Not provided at time of registration
Overall study start date	01/02/2004
Completion date	01/07/2006

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	Pilot study; 3 groups of 11.
Key inclusion criteria	Not provided at time of registration
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/02/2004
Date of final enrolment	01/07/2006

St Pauls Eye Unit

Liverpool
L7 8XP
United Kingdom

Department of Health
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website	http://www.dh.gov.uk/Home/fs/en

Government

Royal Liverpool and Broadgreen University Hospitals Trust (UK)

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	12/07/2007		Yes	No