Condition category
Circulatory System
Date applied
23/01/2004
Date assigned
23/01/2004
Last edited
22/02/2008
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Steve Goodacre

ORCID ID

Contact details

Medical Care Research Unit
School of Health and Related Research
University of Sheffield
Regent Court
30 Regent Street
Sheffield
S1 4DA
United Kingdom
+44 (0)114 222 0842
s.goodacre@sheffield.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

RBP 00XX4

Study information

Scientific title

Acronym

ESCAPE

Study hypothesis

To measure the effect of availability of a Chest Pain Observation Unit upon outcome of patients attending with chest pain and measure the cost-effectiveness of a Chest Pain Observation Unit in a UK hospital.

Ethics approval

The study protocol was approved by the North Sheffield Research Ethics Committee.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Quality of life

Patient information sheet

Condition

Cardiovascular diseases: Heart disease

Intervention

1. Chest pain observation unit
2. Standard care

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Proportion of cases of myocardial infarction (MI) inappropriately sent home by 72 hours after attendance.

Secondary outcome measures

1. Quality of life, health and patients satisfaction at one month
2. Hospital reattendance rates and adverse cardiac event rates at one year and hospital resource usage over one year
3. Quality of life questionnaire (36-item short form health survey [SF-36]) anxiety/depression scales (Hospital anxiety and depression scale [HADS]) and health utility scale (EQ-5D)

Overall trial start date

05/02/2001

Overall trial end date

31/01/2002

Reason abandoned

Eligibility

Participant inclusion criteria

900 patients attending accident and emergency with a primary complaint of chest pain between 7.00am and 7.00pm.

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

900

Participant exclusion criteria

1. Electrocardiogram (ECG) abnormality
2. Unstable angina
3. Co-morbidity
4. Less than 25 years
5. Unable to consent

Recruitment start date

05/02/2001

Recruitment end date

31/01/2002

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Medical Care Research Unit
Sheffield
S1 4DA
United Kingdom

Sponsor information

Organisation

NHS R&D Regional Programme Register - Department of Health (UK)

Sponsor details

The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)20 7307 2622
dhmail@doh.gsi.org.uk

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Government

Funder name

NHS Executive Trent (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Results in http://www.ncbi.nlm.nih.gov/pubmed/15283863

Publication citations

  1. Results

    Goodacre S, Nicholl J, A randomised controlled trial to measure the effect of chest pain unit care upon anxiety, depression, and health-related quality of life [ISRCTN85078221]., Health Qual Life Outcomes, 2004, 2, 39, doi: 10.1186/1477-7525-2-39.

Additional files

Editorial Notes