Single centre randomised controlled trial (RCT) of a chest pain observation unit versus routine care

ISRCTN ISRCTN85078221
DOI https://doi.org/10.1186/ISRCTN85078221
Secondary identifying numbers RBP 00XX4
Submission date
23/01/2004
Registration date
23/01/2004
Last edited
22/02/2008
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Steve Goodacre
Scientific

Medical Care Research Unit
School of Health and Related Research
University of Sheffield
Regent Court
30 Regent Street
Sheffield
S1 4DA
United Kingdom

Phone +44 (0)114 222 0842
Email s.goodacre@sheffield.ac.uk

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Hospital
Study typeQuality of life
Scientific title
Study acronymESCAPE
Study objectivesTo measure the effect of availability of a Chest Pain Observation Unit upon outcome of patients attending with chest pain and measure the cost-effectiveness of a Chest Pain Observation Unit in a UK hospital.
Ethics approval(s)The study protocol was approved by the North Sheffield Research Ethics Committee.
Health condition(s) or problem(s) studiedCardiovascular diseases: Heart disease
Intervention1. Chest pain observation unit
2. Standard care
Intervention typeOther
Primary outcome measureProportion of cases of myocardial infarction (MI) inappropriately sent home by 72 hours after attendance.
Secondary outcome measures1. Quality of life, health and patients satisfaction at one month
2. Hospital reattendance rates and adverse cardiac event rates at one year and hospital resource usage over one year
3. Quality of life questionnaire (36-item short form health survey [SF-36]) anxiety/depression scales (Hospital anxiety and depression scale [HADS]) and health utility scale (EQ-5D)
Overall study start date05/02/2001
Completion date31/01/2002

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexNot Specified
Target number of participants900
Key inclusion criteria900 patients attending accident and emergency with a primary complaint of chest pain between 7.00am and 7.00pm.
Key exclusion criteria1. Electrocardiogram (ECG) abnormality
2. Unstable angina
3. Co-morbidity
4. Less than 25 years
5. Unable to consent
Date of first enrolment05/02/2001
Date of final enrolment31/01/2002

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

Medical Care Research Unit
Sheffield
S1 4DA
United Kingdom

Sponsor information

NHS R&D Regional Programme Register - Department of Health (UK)
Government

The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Phone +44 (0)20 7307 2622
Email dhmail@doh.gsi.org.uk
Website http://www.doh.gov.uk

Funders

Funder type

Government

NHS Executive Trent (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article Results 29/07/2004 Yes No