Contact information
Type
Scientific
Primary contact
Dr Steve Goodacre
ORCID ID
Contact details
Medical Care Research Unit
School of Health and Related Research
University of Sheffield
Regent Court
30 Regent Street
Sheffield
S1 4DA
United Kingdom
+44 (0)114 222 0842
s.goodacre@sheffield.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
RBP 00XX4
Study information
Scientific title
Acronym
ESCAPE
Study hypothesis
To measure the effect of availability of a Chest Pain Observation Unit upon outcome of patients attending with chest pain and measure the cost-effectiveness of a Chest Pain Observation Unit in a UK hospital.
Ethics approval
The study protocol was approved by the North Sheffield Research Ethics Committee.
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Quality of life
Patient information sheet
Condition
Cardiovascular diseases: Heart disease
Intervention
1. Chest pain observation unit
2. Standard care
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
Proportion of cases of myocardial infarction (MI) inappropriately sent home by 72 hours after attendance.
Secondary outcome measures
1. Quality of life, health and patients satisfaction at one month
2. Hospital reattendance rates and adverse cardiac event rates at one year and hospital resource usage over one year
3. Quality of life questionnaire (36-item short form health survey [SF-36]) anxiety/depression scales (Hospital anxiety and depression scale [HADS]) and health utility scale (EQ-5D)
Overall trial start date
05/02/2001
Overall trial end date
31/01/2002
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
900 patients attending accident and emergency with a primary complaint of chest pain between 7.00am and 7.00pm.
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
900
Participant exclusion criteria
1. Electrocardiogram (ECG) abnormality
2. Unstable angina
3. Co-morbidity
4. Less than 25 years
5. Unable to consent
Recruitment start date
05/02/2001
Recruitment end date
31/01/2002
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Medical Care Research Unit
Sheffield
S1 4DA
United Kingdom
Sponsor information
Organisation
NHS R&D Regional Programme Register - Department of Health (UK)
Sponsor details
The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)20 7307 2622
dhmail@doh.gsi.org.uk
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
NHS Executive Trent (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
Results in http://www.ncbi.nlm.nih.gov/pubmed/15283863
Publication citations
-
Results
Goodacre S, Nicholl J, A randomised controlled trial to measure the effect of chest pain unit care upon anxiety, depression, and health-related quality of life [ISRCTN85078221]., Health Qual Life Outcomes, 2004, 2, 39, doi: 10.1186/1477-7525-2-39.