Single centre randomised controlled trial (RCT) of a chest pain observation unit versus routine care
| ISRCTN | ISRCTN85078221 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN85078221 |
| Secondary identifying numbers | RBP 00XX4 |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 22/02/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Steve Goodacre
Scientific
Scientific
Medical Care Research Unit
School of Health and Related Research
University of Sheffield
Regent Court
30 Regent Street
Sheffield
S1 4DA
United Kingdom
| Phone | +44 (0)114 222 0842 |
|---|---|
| s.goodacre@sheffield.ac.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Quality of life |
| Scientific title | |
| Study acronym | ESCAPE |
| Study objectives | To measure the effect of availability of a Chest Pain Observation Unit upon outcome of patients attending with chest pain and measure the cost-effectiveness of a Chest Pain Observation Unit in a UK hospital. |
| Ethics approval(s) | The study protocol was approved by the North Sheffield Research Ethics Committee. |
| Health condition(s) or problem(s) studied | Cardiovascular diseases: Heart disease |
| Intervention | 1. Chest pain observation unit 2. Standard care |
| Intervention type | Other |
| Primary outcome measure | Proportion of cases of myocardial infarction (MI) inappropriately sent home by 72 hours after attendance. |
| Secondary outcome measures | 1. Quality of life, health and patients satisfaction at one month 2. Hospital reattendance rates and adverse cardiac event rates at one year and hospital resource usage over one year 3. Quality of life questionnaire (36-item short form health survey [SF-36]) anxiety/depression scales (Hospital anxiety and depression scale [HADS]) and health utility scale (EQ-5D) |
| Overall study start date | 05/02/2001 |
| Completion date | 31/01/2002 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 900 |
| Key inclusion criteria | 900 patients attending accident and emergency with a primary complaint of chest pain between 7.00am and 7.00pm. |
| Key exclusion criteria | 1. Electrocardiogram (ECG) abnormality 2. Unstable angina 3. Co-morbidity 4. Less than 25 years 5. Unable to consent |
| Date of first enrolment | 05/02/2001 |
| Date of final enrolment | 31/01/2002 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Medical Care Research Unit
Sheffield
S1 4DA
United Kingdom
S1 4DA
United Kingdom
Sponsor information
NHS R&D Regional Programme Register - Department of Health (UK)
Government
Government
The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Phone | +44 (0)20 7307 2622 |
|---|---|
| dhmail@doh.gsi.org.uk | |
| Website | http://www.doh.gov.uk |
Funders
Funder type
Government
NHS Executive Trent (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | Results | 29/07/2004 | Yes | No |
