The effect of prostanoid precursors on platelet angiotensin II binding
| ISRCTN | ISRCTN85634342 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN85634342 |
| Secondary identifying numbers | N0158024607 |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 15/01/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr PMS O'Brien
Scientific
Scientific
Obstetrics and Gynaecology Academic Department
Maternity Block
City General
Newcastle Road
Stoke-on-Trent
ST4 6QG
United Kingdom
| Phone | +44 (0)1782 554998 |
|---|
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | To determine the effect of fish oil dietary supplements and aspirin on platelet angiotensin II binding. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular: Hypertension |
| Intervention | Normotensive and hypertensive women will be randomly allocated in a double blind manner to one of the four groups: fish oil, aspirin, fish oil and aspirin and placebo. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | fish oil, aspirin |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/06/1994 |
| Completion date | 01/06/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Target number of participants | 128 |
| Key inclusion criteria | 128 women in total will be recruited, 32 patients to each of the four treatment arms. Half the women will be hypertensive and the other half normotensive. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/06/1994 |
| Date of final enrolment | 01/06/2004 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Obstetrics and Gynaecology Academic Department
Stoke-on-Trent
ST4 6QG
United Kingdom
ST4 6QG
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.doh.gov.uk |
|---|
Funders
Funder type
Government
North Staffordshire Research and Development Consortium (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/01/1999 | Yes | No |
