Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0158024607
Study information
Scientific title
Acronym
Study hypothesis
To determine the effect of fish oil dietary supplements and aspirin on platelet angiotensin II binding.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Cardiovascular: Hypertension
Intervention
Normotensive and hypertensive women will be randomly allocated in a double blind manner to one of the four groups: fish oil, aspirin, fish oil and aspirin and placebo.
Intervention type
Drug
Phase
Not Specified
Drug names
fish oil, aspirin
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/06/1994
Overall trial end date
01/06/2004
Reason abandoned
Eligibility
Participant inclusion criteria
128 women in total will be recruited, 32 patients to each of the four treatment arms. Half the women will be hypertensive and the other half normotensive.
Participant type
Patient
Age group
Adult
Gender
Female
Target number of participants
128
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/06/1994
Recruitment end date
01/06/2004
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Obstetrics and Gynaecology Academic Department
Stoke-on-Trent
ST4 6QG
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
North Staffordshire Research and Development Consortium (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
1999 results in http://www.ncbi.nlm.nih.gov/pubmed/15512224
Publication citations
-
Results
Walker T, Singh PK, Wyatt KM, O'Brien PM, The effect of prostanoid precursors and inhibitors on platelet angiotensin II binding., J Obstet Gynaecol, 1999, 19, 1, 56-58, doi: 10.1080/01443619965985.