Condition category
Nutritional, Metabolic, Endocrine
Date applied
21/08/2017
Date assigned
21/08/2017
Last edited
21/08/2017
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Background and study aims
Wasting (having a low weight-for-height) and stunting (having a low height-for-age) are common and are implicated in the deaths of almost two million children each year. Wasting and stunting tend to be addressed as separate issues despite evidence of common causes and the fact that many children suffer simultaneously from both conditions. The aim of this study is to examine the size of the overlap between wasted and stunted children to determine the degree of overlap and the association with underweight children.

Who can participate?
Children aged 6-59 months

What does the study involve?
A database of surveys is created containing data for almost 1.8 million children. This is analysed to determine the overlap between sets of wasted, stunted, and underweight children; the association between being wasted and being stunted; the severity of wasting and stunting; and the prevalence of wasting and stunting by age and sex.

What are the possible benefits and risks of participating?
There are no benefits or risks to the children who are measured. The benefit is to the international community concerned with addressing all forms of child undernutrition.

Where is the study run from?
Emergency Nutrition Network (UK)

When is the study starting and how long is it expected to run for?
January 1992 to December 2015

Who is funding the study?
1. US Agency for International Development (USA)
2. Irish Aid (Ireland)

Who is the main contact?
Ms Carmel Dolan

Trial website

Contact information

Type

Scientific

Primary contact

Ms Carmel Dolan

ORCID ID

Contact details

32 Leopold Street
Oxford
OX4 1TW
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Children who are both wasted and stunted are also underweight and have a high risk of death – policy implications

Acronym

Study hypothesis

This study examined the magnitude of overlap between wasted and stunted children to determine the degree of overlap and the association with underweight children.

Ethics approval

This is an observational study so does not need ethical approval. All data was anonymous and was secondary and readily available for further analysis. There were no human or animal subjects.

Study design

Observational cross-sectional study

Primary study design

Observational

Secondary study design

Cross sectional study

Trial setting

Other

Trial type

Other

Patient information sheet

Not available in web format, please use the contact details to request a patient information sheet

Condition

Nutrition

Intervention

A database of cross-sectional survey datasets containing data for almost 1.8 million children was compiled. This was analysed to determine the intersection between sets of wasted, stunted, and underweight children; the association between being wasted and being stunted; the severity of wasting and stunting in WaSt children; and the prevalence of WaSt by age and sex. An additional analysis of the WHO Growth Standards sought the maximum possible weight-for-age z-score for WaSt children.

Intervention type

Other

Phase

Drug names

Primary outcome measures

Overlap between wasted, stunted and underweight children as measured by <-2SD WHZ, HAZ, WAZ

Secondary outcome measures

Degree of concurrence i.e. <-2SDWHZ AND ,-2SDHAZ in children and by age (6-59 months) and by sex (male/female)

Overall trial start date

01/01/1992

Overall trial end date

01/12/2015

Reason abandoned

Eligibility

Participant inclusion criteria

1. 6-59 month old children
2. Males and females

Participant type

All

Age group

Child

Gender

Both

Target number of participants

1,796,991 children

Participant exclusion criteria

Children over 59 months of age

Recruitment start date

01/01/1992

Recruitment end date

01/12/2015

Locations

Countries of recruitment

Afghanistan, Albania, Algeria, American Samoa, Angola, Bahrain, Bangladesh, Benin, Burkina Faso, Burundi, Cambodia, Cameroon, Cape Verde, Central African Republic, Chad, Congo, Congo, Democratic Republic, Cote d'Ivoire, Djibouti, Ecuador, Equatorial Guinea, Eritrea, Ethiopia, Gabon, Gambia, Ghana, Guinea-Bissau, Haiti, India, Indonesia, Kenya, Laos, Lesotho, Liberia, Madagascar, Malawi, Mali, Mauritania, Mozambique, Myanmar, Namibia, Nepal, Niger, Nigeria, Pakistan, Rwanda, Senegal, Sierra Leone, Somalia, South Sudan, Sudan, Tajikistan, Tanzania, Timor-Leste, Uganda, Yemen, Zambia, Zimbabwe

Trial participating centre

-
-

Sponsor information

Organisation

Emergency Nutrition Network

Sponsor details

32 Leopold Street
Oxford
OX4 1TW
United Kingdom

Sponsor type

Charity

Website

http://www.ennonline.net/

Funders

Funder type

Government

Funder name

United States Agency for International Development, 295 Grant Number: ENN AID-OFDA-G-15-00190

Alternative name(s)

U.S. Agency for International Development, USAID

Funding Body Type

government organisation

Funding Body Subtype

federal/national government

Location

United States of America

Funder name

Irish Aid

Alternative name(s)

Funding Body Type

government organisation

Funding Body Subtype

federal/national government

Location

Ireland

Results and Publications

Publication and dissemination plan

The study is being submitted to a high impact peer reviewed journal and once accepted the trialists will ensure open access and at a later stage disseminate through their organization's global network and via international meetings/conferences.


IPD sharing statement
These are merged datasets which many international organisations feed into when the surveys are complete. The data is anonymous so there is no risk of invading confidentiality. These are quite old SMART surveys that might not be used again. The agencies also have the data and the source agency is acknowledged in the paper. The data is officially ‘owned’ by the donors who funded the surveys originally and they insist on open access data exactly for the purpose of further analysis. The lead author is a senior analyst who has access to the datasets and has used the data for previous well known peer reviewed publications.

Intention to publish date

21/11/2017

Participant level data

Stored in repository

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes