Condition category
Circulatory System
Date applied
18/11/2001
Date assigned
18/11/2001
Last edited
03/10/2007
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Professor RA Kenny

ORCID ID

Contact details

Cardiovascular Investigation Unit
Ward 15 Offices
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE14 4AH
United Kingdom
+44 (0)191 2225316
R.A.Kenny@ncl.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

PG/96150

Study information

Scientific title

Acronym

UKPACE

Study hypothesis

Does dual chamber pacing improve the quality of life and cognitive function of elderly patients with complete heart block?

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Sinus syndrome and atrioventricular nodal disease

Intervention

Mode of pacemaker at implantation, i.e., single chamber ventricular or physiological.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

30/01/1997

Overall trial end date

30/01/1999

Reason abandoned

Eligibility

Participant inclusion criteria

Patients over the age of 70 with atrioventricular block treated by implantation of pacemaker.

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

Not provided at time of registration

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

30/01/1997

Recruitment end date

30/01/1999

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Cardiovascular Investigation Unit
Newcastle upon Tyne
NE14 4AH
United Kingdom

Sponsor information

Organisation

British Heart Foundation (UK)

Sponsor details

14 Fitzhardinge Street
London
W1H 6DH
United Kingdom
+44 (0)20 7935 0185
research@bhf.org.uk

Sponsor type

Charity

Website

http://www.bhf.org.uk/

Funders

Funder type

Charity

Funder name

British Heart Foundation (UK) (ref: PG/96150)

Alternative name(s)

BHF

Funding Body Type

private sector organisation

Funding Body Subtype

foundation

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Protocol of entire UKPACE study in http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9391280

Results in http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15580719

Publication citations

  1. Protocol of entire UKPACE study

    Toff WD, Skehan JD, De Bono DP, Camm AJ, The United Kingdom pacing and cardiovascular events (UKPACE) trial. United Kingdom Pacing and Cardiovascular Events., Heart, 1997, 78, 3, 221-223.

  2. Results

    Gribbin GM, Kenny RA, McCue P, Toff WD, Bexton RS, McComb JM, Individualised quality of life after pacing. Does mode matter?, Europace, 2004, 6, 6, 552-560.

Additional files

Editorial Notes