Contact information
Type
Scientific
Primary contact
Professor RA Kenny
ORCID ID
Contact details
Cardiovascular Investigation Unit
Ward 15 Offices
Royal Victoria Infirmary
Queen Victoria Road
Newcastle upon Tyne
NE14 4AH
United Kingdom
+44 (0)191 2225316
R.A.Kenny@ncl.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
PG/96150
Study information
Scientific title
Acronym
UKPACE
Study hypothesis
Does dual chamber pacing improve the quality of life and cognitive function of elderly patients with complete heart block?
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Sinus syndrome and atrioventricular nodal disease
Intervention
Mode of pacemaker at implantation, i.e., single chamber ventricular or physiological.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
30/01/1997
Overall trial end date
30/01/1999
Reason abandoned
Eligibility
Participant inclusion criteria
Patients over the age of 70 with atrioventricular block treated by implantation of pacemaker.
Participant type
Patient
Age group
Senior
Gender
Both
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
30/01/1997
Recruitment end date
30/01/1999
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Cardiovascular Investigation Unit
Newcastle upon Tyne
NE14 4AH
United Kingdom
Sponsor information
Organisation
British Heart Foundation (UK)
Sponsor details
14 Fitzhardinge Street
London
W1H 6DH
United Kingdom
+44 (0)20 7935 0185
research@bhf.org.uk
Sponsor type
Charity
Website
Funders
Funder type
Charity
Funder name
British Heart Foundation (UK) (ref: PG/96150)
Alternative name(s)
BHF
Funding Body Type
private sector organisation
Funding Body Subtype
foundation
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
Protocol of entire UKPACE study in http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9391280
Results in http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15580719
Publication citations
-
Protocol of entire UKPACE study
Toff WD, Skehan JD, De Bono DP, Camm AJ, The United Kingdom pacing and cardiovascular events (UKPACE) trial. United Kingdom Pacing and Cardiovascular Events., Heart, 1997, 78, 3, 221-223.
-
Results
Gribbin GM, Kenny RA, McCue P, Toff WD, Bexton RS, McComb JM, Individualised quality of life after pacing. Does mode matter?, Europace, 2004, 6, 6, 552-560.