A Trial to Establish the Role of Leukocyte Concentration and Tissue Type of Transfused Blood in Immunomodulation of Patients Undergoing Elective Surgery for Colorectal Cancer

ISRCTN ISRCTN92341395
DOI https://doi.org/10.1186/ISRCTN92341395
Secondary identifying numbers CRBT
Submission date
19/08/2002
Registration date
19/08/2002
Last edited
15/10/2012
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr - -
Scientific

UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Not specified
Study typeNot Specified
Scientific title
Study objectivesNot provided at time of registration
Ethics approval(s)Not provided at time of registration
Health condition(s) or problem(s) studiedColorectal cancer
Intervention1. Arm A: Surgery without transfusion
2. Arm B: Surgery with standard blood transfusion
3. Arm C: Surgery with leucodepleted blood transfusion
Intervention typeOther
Primary outcome measureNot provided at time of registration
Secondary outcome measuresNot provided at time of registration
Overall study start date01/01/2000
Completion date31/12/2005

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexNot Specified
Target number of participantsNot provided at time of registration
Key inclusion criteria1. Patients undergoing elective resection of colorectal carcinoma
2. No transfusion of blood in the 6 months preceding the operation
3. No transfusion of blood prior to the first postoperative sample
4. No concurrent immunosuppressive medication
5. No previous transfusion reaction requiring cessation of transfusion
Key exclusion criteriaNot provided at time of registration
Date of first enrolment01/01/2000
Date of final enrolment31/12/2005

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

UKCCCR Register Co-ordinator
London
NW1 2DA
United Kingdom

Sponsor information

Leicester General Hospital (UK)
Hospital/treatment centre

Gwendolen Road
Leicester
LE5 4PW
England
United Kingdom

ROR logo "ROR" https://ror.org/02zg49d29

Funders

Funder type

Hospital/treatment centre

Leicester General Hospital (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan