A Trial to Establish the Role of Leukocyte Concentration and Tissue Type of Transfused Blood in Immunomodulation of Patients Undergoing Elective Surgery for Colorectal Cancer
ISRCTN | ISRCTN92341395 |
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DOI | https://doi.org/10.1186/ISRCTN92341395 |
Secondary identifying numbers | CRBT |
- Submission date
- 19/08/2002
- Registration date
- 19/08/2002
- Last edited
- 15/10/2012
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr - -
Scientific
Scientific
UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom
Study information
Study design | Randomised controlled trial |
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Primary study design | Interventional |
Secondary study design | Randomised controlled trial |
Study setting(s) | Not specified |
Study type | Not Specified |
Scientific title | |
Study objectives | Not provided at time of registration |
Ethics approval(s) | Not provided at time of registration |
Health condition(s) or problem(s) studied | Colorectal cancer |
Intervention | 1. Arm A: Surgery without transfusion 2. Arm B: Surgery with standard blood transfusion 3. Arm C: Surgery with leucodepleted blood transfusion |
Intervention type | Other |
Primary outcome measure | Not provided at time of registration |
Secondary outcome measures | Not provided at time of registration |
Overall study start date | 01/01/2000 |
Completion date | 31/12/2005 |
Eligibility
Participant type(s) | Patient |
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Age group | Not Specified |
Sex | Not Specified |
Target number of participants | Not provided at time of registration |
Key inclusion criteria | 1. Patients undergoing elective resection of colorectal carcinoma 2. No transfusion of blood in the 6 months preceding the operation 3. No transfusion of blood prior to the first postoperative sample 4. No concurrent immunosuppressive medication 5. No previous transfusion reaction requiring cessation of transfusion |
Key exclusion criteria | Not provided at time of registration |
Date of first enrolment | 01/01/2000 |
Date of final enrolment | 31/12/2005 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
UKCCCR Register Co-ordinator
London
NW1 2DA
United Kingdom
NW1 2DA
United Kingdom
Sponsor information
Leicester General Hospital (UK)
Hospital/treatment centre
Hospital/treatment centre
Gwendolen Road
Leicester
LE5 4PW
England
United Kingdom
https://ror.org/02zg49d29 |
Funders
Funder type
Hospital/treatment centre
Leicester General Hospital (UK)
No information available
Results and Publications
Intention to publish date | |
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Individual participant data (IPD) Intention to share | No |
IPD sharing plan summary | Not provided at time of registration |
Publication and dissemination plan | Not provided at time of registration |
IPD sharing plan |