Condition category
Signs and Symptoms
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
16/12/2014
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr A Guha

ORCID ID

Contact details

Anaesthesia
University Hospital Aintree
Longmoor Lane
Fazakerley
Liverpool
L9 7AL
United Kingdom
+44 (0)151 529 5152 / 5153
abc@email.com

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0025107242

Study information

Scientific title

Nasogastric and intravenous erythromycin as prokinetic in intensive care patients: a randomised controlled study

Acronym

Study hypothesis

Erythromycin's effect on gastric emptying in intensive care

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Signs and Symptoms: Gastric emptying

Intervention

A 5 ml sample of blood will be taken for measuring baseline paracetamol content. 1.5 g of soluble paracetamol will be administered to them through their nasogastric tube.
They will then be randomised to receive 250 g of either nasogastric or intravenous erythromycin. Further blood samples (5 ml each time) will be taken at 15, 30, 45, 60, 120, 180 and 240 min after giving paracetamol. These samples will then be sent to the laboratory for assay. After obtaining the data, these will be analysed for statistical significance.

Intervention type

Drug

Phase

Not Applicable

Drug names

Erythromycin

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/01/2002

Overall trial end date

01/07/2003

Reason abandoned

Eligibility

Participant inclusion criteria

Intensive Care patients who will be recruited into the study if they exhibit a failure to absorb nasogastric feed.

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

Not provided at time of registration

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/01/2002

Recruitment end date

01/07/2003

Locations

Countries of recruitment

United Kingdom

Trial participating centre

University Hospital Aintree
Liverpool
L9 7AL
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Hospital/treatment centre

Funder name

Aintree Hospitals NHS Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes