Contact information
Type
Scientific
Primary contact
Dr A Guha
ORCID ID
Contact details
Anaesthesia
University Hospital Aintree
Longmoor Lane
Fazakerley
Liverpool
L9 7AL
United Kingdom
+44 (0)151 529 5152 / 5153
abc@email.com
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0025107242
Study information
Scientific title
Nasogastric and intravenous erythromycin as prokinetic in intensive care patients: a randomised controlled study
Acronym
Study hypothesis
Erythromycin's effect on gastric emptying in intensive care
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Signs and Symptoms: Gastric emptying
Intervention
A 5 ml sample of blood will be taken for measuring baseline paracetamol content. 1.5 g of soluble paracetamol will be administered to them through their nasogastric tube.
They will then be randomised to receive 250 g of either nasogastric or intravenous erythromycin. Further blood samples (5 ml each time) will be taken at 15, 30, 45, 60, 120, 180 and 240 min after giving paracetamol. These samples will then be sent to the laboratory for assay. After obtaining the data, these will be analysed for statistical significance.
Intervention type
Drug
Phase
Not Applicable
Drug names
Erythromycin
Primary outcome measure
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/01/2002
Overall trial end date
01/07/2003
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Intensive Care patients who will be recruited into the study if they exhibit a failure to absorb nasogastric feed.
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/01/2002
Recruitment end date
01/07/2003
Locations
Countries of recruitment
United Kingdom
Trial participating centre
University Hospital Aintree
Liverpool
L9 7AL
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Hospital/treatment centre
Funder name
Aintree Hospitals NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list