Condition category
Nervous System Diseases
Date applied
05/07/2005
Date assigned
26/08/2005
Last edited
24/08/2012
Prospective/Retrospective
Prospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof Alistair Burns

ORCID ID

Contact details

Wythenshawe Hospital
Manchester
M23 9LT
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

71887897

Study information

Scientific title

Acronym

WHIFF-AD

Study hypothesis

Aromatherapy is as effective as standard treatment for agitation in Alzheimer's disease

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Treatment

Patient information sheet

Condition

Alzheimer's disease

Intervention

Aromatherapy versus standard treatment

Intervention type

Drug

Phase

Not Specified

Drug names

Aromatherapy

Primary outcome measures

Reduction in agitation

Secondary outcome measures

Side effect profile

Overall trial start date

01/02/2006

Overall trial end date

01/02/2009

Reason abandoned

Eligibility

Participant inclusion criteria

Alzheimer's disease with agitation

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

150

Participant exclusion criteria

Failure to meet inclusion criteria

Recruitment start date

01/02/2006

Recruitment end date

01/02/2009

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Wythenshawe Hospital
Manchester
M23 9LT
United Kingdom

Sponsor information

Organisation

Alzheimer's Society (UK)

Sponsor details

10 Greencoat Place
London
SW1P 7PH
United Kingdom

Sponsor type

Charity

Website

Funders

Funder type

Charity

Funder name

Alzheimer's Society

Alternative name(s)

Funding Body Type

private sector organisation

Funding Body Subtype

professional associations and societies

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 2011 results in http://www.ncbi.nlm.nih.gov/pubmed/21335973

Publication citations

  1. Results

    Burns A, Perry E, Holmes C, Francis P, Morris J, Howes MJ, Chazot P, Lees G, Ballard C, A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitation in Alzheimer's disease., Dement Geriatr Cogn Disord, 2011, 31, 2, 158-164, doi: 10.1159/000324438.

Additional files

Editorial Notes