Can systemic and pulmonary antioxidants become depleted after regular paracetamol intake?
| ISRCTN | ISRCTN99544972 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN99544972 |
| Protocol serial number | N0046131423 |
| Sponsor | Department of Health |
| Funder | Birmingham Heartlands and Solihull NHS Trust (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 01/05/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Miss Sarah Manney
Scientific
Scientific
Research & Development, Lincoln House
Heart of England NHS Foundation Trust
Birmingham Heartlands Hospital
Bordesley Green East
Birmingham
B9 5SS
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised placebo-controlled single-blind crossover study |
| Secondary study design | Randomised controlled trial |
| Scientific title | Can systemic and pulmonary antioxidants become depleted after regular paracetamol intake? |
| Study objectives | To determine the impact of paracetamol intake on changes in serum markers of total antioxidant activity and glutathione concentrations. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Depletion of systemic and pulmonary antioxidants |
| Intervention | Paracetamol vs placebo |
| Intervention type | Drug |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Paracetamol |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/02/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 20 |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 30/11/2003 |
| Date of final enrolment | 01/02/2004 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Birmingham Heartlands Hospital
Birmingham
B9 5SS
United Kingdom
B9 5SS
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
