Can systemic and pulmonary antioxidants become depleted after regular paracetamol intake?
| ISRCTN | ISRCTN99544972 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN99544972 |
| Secondary identifying numbers | N0046131423 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 01/05/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Miss Sarah Manney
Scientific
Scientific
Research & Development, Lincoln House
Heart of England NHS Foundation Trust
Birmingham Heartlands Hospital
Bordesley Green East
Birmingham
B9 5SS
United Kingdom
Study information
| Study design | Randomised placebo-controlled single-blind crossover study |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Other |
| Study type | Other |
| Scientific title | Can systemic and pulmonary antioxidants become depleted after regular paracetamol intake? |
| Study objectives | To determine the impact of paracetamol intake on changes in serum markers of total antioxidant activity and glutathione concentrations. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Depletion of systemic and pulmonary antioxidants |
| Intervention | Paracetamol vs placebo |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Paracetamol |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 30/11/2003 |
| Completion date | 01/02/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 20 |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 30/11/2003 |
| Date of final enrolment | 01/02/2004 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Birmingham Heartlands Hospital
Birmingham
B9 5SS
United Kingdom
B9 5SS
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Government
Birmingham Heartlands and Solihull NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
