Low-dose doxycycline in the treatment of periodontitis in smokers
| ISRCTN | ISRCTN11033714 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN11033714 |
| Protocol serial number | N/A |
| Sponsor | CollaGenex Pharmaceuticals Inc. (USA) |
| Funder | Mainly self-supported: design, conduct, analysis and reporting are independent of industry. Biochemical analyses funded by CollaGenex Inc. |
- Submission date
- 15/10/2002
- Registration date
- 15/10/2002
- Last edited
- 24/11/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Other
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Ian Needleman
Scientific
Scientific
Department of Periodontology
Eastman Dental Institute for Oral Health Care Sciences
University College London
256 Gray's Inn Road
London
WC1X 8LD
United Kingdom
| Phone | +44 (0) 20 7915 2340 |
|---|---|
| i.needleman@eastman.ucl.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Not provided at time of registration. |
| Ethics approval(s) | Not provided at time of registration. |
| Health condition(s) or problem(s) studied | Periodontology |
| Intervention | 1. Non-surgical periodontal therapy plus twice daily 20 mg doxycycline for 3 months 2. Non-surgical periodontal therapy plus twice daily placebo for 3 months |
| Intervention type | Other |
| Primary outcome measure(s) |
Not provided at time of registration. |
| Key secondary outcome measure(s) |
Not provided at time of registration. |
| Completion date | 15/10/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | 1. Smokers unable to quit 2. Moderate-severe chronic periodontitis 3. Age 30-70 |
| Key exclusion criteria | Not provided at time of registration. |
| Date of first enrolment | 15/10/2000 |
| Date of final enrolment | 15/10/2005 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Department of Periodontology
London
WC1X 8LD
United Kingdom
WC1X 8LD
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/04/2007 | Yes | No |
