Stress reactivity in insomnia
| ISRCTN | ISRCTN14242553 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN14242553 |
| Sponsor | Research Council of Finland |
| Funder | Research Council of Finland |
- Submission date
- 03/10/2026
- Registration date
- 20/10/2026
- Last edited
- 19/10/2026
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Anu-Katriina Pesonen
Scientific, Public, Principal investigator
Scientific, Public, Principal investigator
Haartmaninkatu 3
Helsinki
00014
Finland
| Phone | +358 (0)407544942 |
|---|---|
| anukatriina.pesonen@helsinki.fi |
Study information
| Primary study design | Interventional |
|---|---|
| Allocation | Randomized controlled trial |
| Masking | Open (masking not used) |
| Control | Uncontrolled |
| Assignment | Crossover |
| Purpose | Basic science, Diagnostic, Treatment |
| Scientific title | Sleep and brain plasticity: effects of stress and perceived insomnia |
| Study acronym | Sleepemotion 5 |
| Study objectives | RQ1: How sleep EEG characteristics ( including the quality and continuity of REM sleep, sleep EEG spectral power, sleep stage transitions), cardiac activity during sleep and individual stress reactivity profiles relate to insomnia and sleep misperception in individuals having paradoxical insomnia (underestimation of sleep time)? RQ2: Does a pre-sleep relaxation exercise improve sleep in individuals with insomnia (including the subtype of paradoxical insomnia)? RQ3: Does sleep-related memory consolidation facilitate the updating of affective social appraisals and how these are related to different brain and cardiac activity profiles during sleep and prior to sleep? |
| Ethics approval(s) |
Approved 20/06/2025, Ethical committee of medicine, University of Helsinki (Yliopistokatu 4, Helsinki, 00014, Finland; +358 (0)294129528; uni-help@helsinki.fi), ref: 2025/17 |
| Health condition(s) or problem(s) studied | Insomnia |
| Intervention | 1. Yoga nidra audio prior to sleep in a within subject cross-over design 2. Control condition: no audio Random allocation to order Night A and Night B using simple randomization |
| Intervention type | Behavioural |
| Primary outcome measure(s) |
|
| Key secondary outcome measure(s) | |
| Completion date | 15/10/2026 |
Eligibility
| Participant type(s) | |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Upper age limit | 55 Years |
| Sex | All |
| Target sample size at registration | 74 |
| Total final enrolment | 74 |
| Key inclusion criteria | 1. Self-declared insomnia by ICD-10 criteria 2. Controls: no insomnia |
| Key exclusion criteria | 1. Other chronic sleep disorder 2. Medication that affects sleep |
| Date of first enrolment | 01/09/2025 |
| Date of final enrolment | 30/06/2026 |
Locations
Countries of recruitment
- Finland
Study participating centres
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|
Editorial Notes
19/10/2026: Study's existence confirmed by the ethical committee of medicine, University of Helsinki.
