Rehabilitation after myocardial infarction: multicentre randomised controlled trial
| ISRCTN | ISRCTN27265832 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN27265832 |
| Protocol serial number | RM19 |
| Sponsor | Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK) |
| Funder | NHS Cardiovascular Disease and Stroke National Research and Development Programme (UK) |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 25/07/2011
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Robert West
Scientific
Scientific
University of Wales College of Medicine
Department of Cardiology
WHRI Building
Heath Park
Cardiff
C4 4 XN
United Kingdom
| Phone | +44 (0)1222 747747 |
|---|
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | There is little evidence for effectiveness of cardiac rehabilitation following acute myocardial infarction as currently provided in the NHS and in the context of modern therapeutic practice. There are few recent trials and historic trials may be of little relevance, since treatments in cardiac care units, with thrombolysis, aspirin, ß blocker, ACE inhibitor and statins have changed greatly in the past thirty years. The principal objective was to determine the effectiveness of programmes of cardiac rehabilitation, as currently provided and in the current clinical context. The trial aimed to measure the effect of rehabilitation on mortality, morbidity and quality of life of patients following myocardial infarction. Further aims included identification of programmes that are more or less effective and of characteristics of patients who benefit more or less from cardiac rehabilitation and to estimate costs of cardiac rehabilitation. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular diseases: Heart disease |
| Intervention | 1. Comprehensive cardiac rehabilitation 2. Standard care |
| Intervention type | Other |
| Primary outcome measure(s) |
Outcomes at one year included mortality, morbidity, cardiac medication, health service use, psychological wellbeing and quality of life on standard scales, cardiac risk factors, including smoking, drinking, diet and leisure time activity. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/04/2000 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/04/1996 |
| Date of final enrolment | 01/04/2000 |
Locations
Countries of recruitment
- United Kingdom
Study participating centre
University of Wales College of Medicine
Cardiff
C4 4 XN
United Kingdom
C4 4 XN
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 14/12/1996 | Yes | No |
