The effects of fentanyl, alfentanil and remifentanil on the cardiovascular responses during rigid bronchoscopy

ISRCTN	ISRCTN31439885
DOI	https://doi.org/10.1186/ISRCTN31439885
Protocol serial number	N0185146397
Sponsor	Department of Health
Funder	Plymouth Hospitals NHS Trust (UK), NHS R&D Support Funding

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Dr S Dudnikov
Scientific

Department of Anaesthesia
Derriford Hospital
Plymouth
PL6 8DH
United Kingdom

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	We are planning to investigate the effects of fentanyl, alfentanil and remifentanil on the cardiovascular responses during rigid bronchoscopy.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Cardiovascular:
Intervention	Patients undergoing rigid bronchoscopy will be randomised into the three drug groups. Measurement of muscle relaxation, arterial blood pressure and heart rate.
Intervention type	Other
Primary outcome measure(s)	Changes in arterial blood pressures and heart rate.
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	25/03/2004

Participant type(s)	Patient
Age group	Adult
Sex	Not Specified
Target sample size at registration	60
Key inclusion criteria	60 adults
Key exclusion criteria	1. Untreated systemic hypertension with SABP>160mmHg and /or DABP> 105mm Hg 2. Arythmias and heart conduction defects 3. Severe bronchial asthma
Date of first enrolment	25/09/2003
Date of final enrolment	25/03/2004

Department of Anaesthesia

Plymouth
PL6 8DH
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan