Wean earlier and automatically with new technology: a multicentre, pilot randomised controlled study
| ISRCTN | ISRCTN43760151 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN43760151 |
| Protocol serial number | N/A |
| Sponsor | Physician Services Incorporated (Canada) |
| Funders | Physician Services Incorporated (Canada), Draeger Canada (in kind) |
- Submission date
- 03/01/2006
- Registration date
- 30/01/2006
- Last edited
- 31/07/2013
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Karen E. A. Burns
Scientific
Scientific
St Michael's Hospital
30 Bond street
3-075E Queen wing
Toronto
M5B 1W8
Canada
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Multicentre randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | The WEAN Study |
| Study objectives | The primary objective of this multicentre pilot study is to compare automatic and protocolised weaning and to evaluate compliance with the proposed weaning and sedation protocols |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Weaning intubated adults from invasive mechanical ventilation |
| Intervention | Automatic (computer-driven) weaning versus protocolized weaning |
| Intervention type | Other |
| Primary outcome measure(s) |
Compliance with the weaning and sedation protocols |
| Key secondary outcome measure(s) |
1. Acceptance of the weaning and sedation protocols |
| Completion date | 01/06/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 90 |
| Key inclusion criteria | Patients who are invasively ventilated for at least 24 hours |
| Key exclusion criteria | 1. Age < 16 years 2. Tracheotomy 3. Pregnancy 4. Do not intubate (DNI) or do not resuscitate (DNR) patients 5. Planned extubation on the day of study inclusion 6. Planned surgery or procedures within 48 hours of randomization |
| Date of first enrolment | 30/05/2006 |
| Date of final enrolment | 01/06/2006 |
Locations
Countries of recruitment
- Canada
Study participating centre
St Michael's Hospital
Toronto
M5B 1W8
Canada
M5B 1W8
Canada
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/06/2013 | Yes | No | |
| Protocol article | protocol | 04/09/2009 | Yes | No |
