A prospective, multi-centre, randomised trial comparing low-dose aspirin with low-dose aspirin plus low-intensity oral anticoagulation in the primary prevention of thrombosis in patients positive for antiphospholipid antibodies
| ISRCTN | ISRCTN81818945 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN81818945 |
| Protocol serial number | K0554 |
| Sponsor | Arthritis Research Campaign (ARC) (UK) |
| Funder | Arthritis Research Campaign (UK) |
- Submission date
- 04/02/2002
- Registration date
- 04/02/2002
- Last edited
- 08/10/2013
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Munther Khamashta
Scientific
Scientific
Louise Coote Lupus Unit
St Thomas' s Hospital
The Rayne Institute
London
SE1 7EH
United Kingdom
| Phone | +44 (0)20 7928 9292 |
|---|---|
| 106404.2325@compuserve.com |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | ALIAPAS |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Prevention of thrombosis |
| Intervention | Patients will be randomised to either low dose (75 mg) aspirin or low-dose aspirin and low international normalised ratio (INR) warfarin |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Aspirin, warfarin |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/01/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Patients positive for antiphospholipid antibodies |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/09/2000 |
| Date of final enrolment | 01/01/2006 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Louise Coote Lupus Unit
London
SE1 7EH
United Kingdom
SE1 7EH
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/02/2014 | Yes | No |
