A prospective, multi-centre, randomised trial comparing low-dose aspirin with low-dose aspirin plus low-intensity oral anticoagulation in the primary prevention of thrombosis in patients positive for antiphospholipid antibodies
| ISRCTN | ISRCTN81818945 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN81818945 |
| Secondary identifying numbers | K0554 |
- Submission date
- 04/02/2002
- Registration date
- 04/02/2002
- Last edited
- 08/10/2013
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Munther Khamashta
Scientific
Scientific
Louise Coote Lupus Unit
St Thomas' s Hospital
The Rayne Institute
London
SE1 7EH
United Kingdom
| Phone | +44 (0)20 7928 9292 |
|---|---|
| 106404.2325@compuserve.com |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study acronym | ALIAPAS |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Prevention of thrombosis |
| Intervention | Patients will be randomised to either low dose (75 mg) aspirin or low-dose aspirin and low international normalised ratio (INR) warfarin |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Aspirin, warfarin |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/09/2000 |
| Completion date | 01/01/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | Patients positive for antiphospholipid antibodies |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/09/2000 |
| Date of final enrolment | 01/01/2006 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Louise Coote Lupus Unit
London
SE1 7EH
United Kingdom
SE1 7EH
United Kingdom
Sponsor information
Arthritis Research Campaign (ARC) (UK)
Charity
Charity
Copeman House
St Mary's Court
St Mary's Gate
Chesterfield
Derbyshire
S41 7TD
United Kingdom
| info@arc.org.uk | |
| Website | http://www.arc.org.uk |
"ROR" |
https://ror.org/02jkpm469 |
Funders
Funder type
Charity
Arthritis Research Campaign (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/02/2014 | Yes | No |
