A study on the lasting effects of a parenting training programme in rural China on child brain function and development
| ISRCTN | ISRCTN93482544 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN93482544 |
| Sponsor | Minzu University of China |
| Funder | Hupan Modou (HPMD) Foundation |
- Submission date
- 05/07/2026
- Registration date
- 08/07/2026
- Last edited
- 07/07/2026
- Recruitment status
- Recruiting
- Overall study status
- Ongoing
- Condition category
- Other
Plain English summary of protocol
Background and study aims
The first years of life are an important period for children’s brain development and later learning. Previous research suggests that a good caregiving environment, including responsive parenting, parent-child interaction and learning support at home, can help children’s cognitive, language and socio-emotional development. In contrast, stressful or less responsive caregiving environments may increase the risk of poorer child development.
In rural China, some children in early childhood have faced risks of developmental delay. Parenting training programmes can be used to improve the home environment and secure children’s developmental opportunities.
Substantial early childhood development research based on scale-based measurements has emerged, providing important evidence for understanding the effects of early parenting interventions. However, existing studies have mainly focused on caregivers’ parenting behaviours and children’s observable developmental outcomes and therefore have limited capacity to directly reveal the underlying neurobiological mechanisms through which interventions influence child development. Meanwhile, widely used standardized assessment tools for infant and toddler development cannot fully eliminate the potential interference of subjective reporting in causal identification, and their results may also be affected by assessors’ implementation procedures and scoring consistency.
The aim of this study is to evaluate the lasting neurodevelopmental and cognitive outcomes of the "Parenting the Future" programme. This follow-up study compares brain function and developmental outcomes between the intervention and control groups to determine whether the programme exerts sustained effects on children at approximately 10-14 years. By combining child development outcomes with measures of the household caregiving environment, the study explores the potential mechanisms through which early childhood parenting interventions may affect children’s brain function and development.
Who can participate?
Children of any sex may take part with their primary caregivers if they were part of previous early childhood parenting studies carried out by the research team in rural western China. The children must have been aged 6–24 months at baseline and are expected to be about 10–14 years old at the 2026 follow-up. They must also have key baseline information and data from the most recent primary-school follow-up. Families must be contactable, and the child’s parent or legal guardian must provide written informed consent.
The EEG follow-up study will include 270 children and their households. This includes 90 children from the treatment group and 90 from the control group of a large-scale randomised parenting training programme targeting infants aged 6-24 months in nationally designated poverty counties, as well as 90 children from a county government-led parenting intervention programme. Parents or primary caregivers will bring the children to take part in the follow-up assessment.
What does the study involve?
This is a follow-up study. No new parenting intervention, medicine or treatment is given in this study. Children and households take part in a one-time follow-up assessment. The study compares children from "Parenting the Future," including the treatment and control groups of a large-scale randomised parenting intervention targeting infants aged 6–24 months in nationally designated poverty counties, and children from a county government-led parenting training programme.
Children will complete an EEG assessment, involving the resting-state EEG outcome measures and MMN outcome measures. Children will also complete developmental and reading assessments. These include a socio-emotional and behavioral development test, a cognitive test and reading tests.
Parents or caregivers will answer questionnaires about the child’s school situation, family structure, home educational environment, parent-child communication, parenting behaviour, education and health investment, caregiver expectations, caregiver mental health and psychosocial resources. The child’s height and weight will also be measured.
What are the possible benefits and risks of participating?
Households receive a participation payment after completing the survey. Participation may stimulate children’s curiosity about learning and their own development. Besides, the study may help researchers and policymakers better understand whether early parenting support has long-term effects on children’s brain function and development in rural China.
The risks are minimal. EEG is non-invasive, painless, and radiation-free. The EEG equipment only records natural brain signals and does not deliver treatment or medicine. Some children may feel mild discomfort from wearing the EEG cap or from sitting still for a short time. Some participants may feel tired during the assessments or questionnaires. Participants can stop or withdraw at any time.
Personal information will be kept confidential. Study results will be reported in a way that does not identify specific children or households.
Where is the study run from?
The study is managed by Minzu University of China. It is conducted in collaboration with Shaanxi Normal University and Beijing Normal University (China).
When is the study starting and how long is it expected to run for?
July 2026 to December 2028
Who is funding the study?
Hupan Modou Foundation (China)
Who is the main contact?
Prof. Yu Bai, yubai@muc.edu.cn
Contact information
Scientific, Principal investigator, Public
No. 27 Zhongguancun South Street, Haidian District
Beijing
100081
China
| Phone | +86 (0)18600405923 |
|---|---|
| yubai@muc.edu.cn |
Study information
| Primary study design | Observational |
|---|---|
| Observational study design | Cohort study |
| Scientific title | Lasting effects of parenting training interventions for children aged 0–3 in rural China on brain function and developmental outcomes in school-aged children : a follow-up study of cluster-randomised controlled trials |
| Study objectives | The objective of this project is to evaluate the lasting neurodevelopment, socio-emotional and behavioral development, and cognitive outcomes of the “Parenting the Future” programme, an early childhood parenting training programme implemented through a large-scale randomized intervention in rural western China. By comparing brain function and development outcomes between treatment groups and control groups, this follow-up study examines whether early childhood parenting training interventions have lasting effects on children 6-7 years after the end of the intervention. Furthermore, by combining child development outcomes with measures of the household caregiving environment, the study explores the potential mechanisms through which early childhood parenting training interventions may affect children’s brain function. |
| Ethics approval(s) |
Approved 29/06/2026, Biological and Medical Ethics Committee, Minzu University of China (No. 27 South ZhongGuanCun Avenue, Haidian District, Beijing, 100081, China; +86 (0)1068933254; jason@muc.edu.cn), ref: ECMUC2026008CO |
| Health condition(s) or problem(s) studied | Child brain function and development |
| Methodology | Participants will be selected from two previous early childhood parenting training interventions of “Parenting the Future” conducted by the research team in rural western China. The intervention provides caregivers with weekly parenting training, designed to reduce children’s early developmental delays. Trained parenting instructors use an adapted Reach Up and Learn curriculum to teach caregivers age-appropriate, interactive parenting practices. The first programme is a large-scale randomised parenting intervention that targeted infants aged 6-24 months in nationally designated poverty counties. For the present follow-up with EEG assessment, 180 children will be drawn from this study, including 90 children from the treatment group and 90 children from the control group. The second programme is a county government-led parenting intervention programme. A further 90 children will be selected from this programme. The total follow-up sample will therefore include 270 children and their households. After written informed consent is obtained from the child’s parent or legal guardian, trained fieldworkers will conduct a one-time follow-up assessment with the child and the primary caregiver. Parents or primary caregivers will bring the children to take part in the assessment. The assessment will collect EEG data and child development data: EEG data are recorded using a 64-channel ANT system in two tasks: (1) a 6-minute resting-state task with eyes-open and eyes-closed conditions, and (2) an auditory mismatch negativity task in which children listen to Chinese syllables while watching a silent film. Child development measures will cover physical growth, cognitive development, socio-emotional and behavioural development, reading development, psychiatric risk, mental health, school adaptation, sibling relationships, expectations and beliefs, and time use. The child questionnaire and interview include WISC and reading tests, preference games, DASS-Y, and OECD-SSES items. The caregiver questionnaire collects information on the child’s household, school situation, parental migration, school behaviour, educational expectations, SDQ, educational investments, health investments, time use, parenting-related beliefs, and other family and caregiver characteristics.Besides, child’s physical growth is measured. After fieldwork, EEG, assessment, and questionnaire data will be checked for quality, completeness, and consistency before analysis. |
| Intervention type | Behavioural |
| Primary outcome measure(s) |
|
| Key secondary outcome measure(s) |
|
| Completion date | 31/12/2028 |
Eligibility
| Participant type(s) | |
|---|---|
| Age group | Child |
| Lower age limit | 10 Years |
| Upper age limit | 14 Years |
| Sex | All |
| Target sample size at registration | 270 |
| Key inclusion criteria | 1. Children of any sex and their primary caregivers who participated in "Parenting the Future" 2. Children drawn from "Parenting the Future", including a treatment group and the control group of one county government-led parenting intervention programme, as well as another large-scale randomised parenting training programme targeting infants aged 6-24 months in nationally designated poverty counties 3. Children who were aged 6-24 months at baseline and children who are approximately 10 to 14 years old at the 2026 follow-up 4. Children with complete information on key baseline covariates and available information from the latest primary-school-stage follow-up 5. Children and caregivers who can be contacted, with written informed consent provided by the child’s parent or legal guardian |
| Key exclusion criteria | 1. The child never participated in any previous parenting training programme of "Parenting the Future" 2. Children who are not selected for the follow-up sample 3. Children whose baseline age is not between 6 and 24 months 4. Children with incomplete information on key baseline covariates, or without available information from the latest primary‑school‑stage follow‑up 5. Children or caregivers who cannot be contacted, or children whose parent or legal guardian does not provide written informed consent |
| Date of first enrolment | 15/07/2026 |
| Date of final enrolment | 30/10/2027 |
Locations
Countries of recruitment
- China
Study participating centres
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|
Editorial Notes
06/07/2026: Study's existence confirmed by the Biological and Medical Ethics Committee, Minzu University of China.