Condition category
Circulatory System
Date applied
23/08/2005
Date assigned
15/09/2005
Last edited
19/11/2007
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

http://www.scottunit.org

Contact information

Type

Scientific

Primary contact

Mr R Alan P Scott

ORCID ID

Contact details

Scott Research Unit
CMEC
St Richard's Hospital
Chichester
PO19 6SE
United Kingdom
+44 (0)1243 831503
scottunit@rws-tr.nhs.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

121/2133 and PA1

Study information

Scientific title

Acronym

Management of AAA

Study hypothesis

To establish prevalence and incidence of AAA in the community. Study effect of screening on mortality from ruptured AAA and on surgical workload and NHS costs.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Abdominal Aortic Aneurysms (AAA)

Intervention

50% randomised to ultrasound screening. Surveillance of patients with detected AAA. All subjects considered for surgical AAA repair if clinical need.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Prevalence and incidence of AAA in men and women 65 - 80 years of age in community.

Secondary outcome measures

The effect of AAA screening on mortality from AAA and AAA surgical workload.

Overall trial start date

01/01/1989

Overall trial end date

31/12/2015

Reason abandoned

Eligibility

Participant inclusion criteria

Men and women aged 65 - 80 years

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

16,000

Participant exclusion criteria

No specific exclusions

Recruitment start date

01/01/1989

Recruitment end date

31/12/2015

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Scott Research Unit
Chichester
PO19 6SE
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)151 794 5900
dot.lambert@dh.gsi.gov.uk

Sponsor type

Government

Website

http://www.dh.gov.uk/en/index.htm

Funders

Funder type

Government

Funder name

Department of Health (UK): 1989 - 1993 (ref: 121/2133)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

DOH NHS R&D Programme for Cardiovascular Disease and Stroke (UK): 1994 - 1999 (ref: PA1)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Charitable donations and 'own account funding' (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Results in http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17514666

Publication citations

  1. Results

    Ashton HA, Gao L, Kim LG, Druce PS, Thompson SG, Scott RA, Fifteen-year follow-up of a randomized clinical trial of ultrasonographic screening for abdominal aortic aneurysms., Br J Surg, 2007, 94, 6, 696-701, doi: 10.1002/bjs.5780.

Additional files

Editorial Notes