Contact information
Type
Scientific
Primary contact
Mr R Alan P Scott
ORCID ID
Contact details
Scott Research Unit
CMEC
St Richard's Hospital
Chichester
PO19 6SE
United Kingdom
+44 (0)1243 831503
scottunit@rws-tr.nhs.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
121/2133 and PA1
Study information
Scientific title
Acronym
Management of AAA
Study hypothesis
To establish prevalence and incidence of AAA in the community. Study effect of screening on mortality from ruptured AAA and on surgical workload and NHS costs.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Abdominal Aortic Aneurysms (AAA)
Intervention
50% randomised to ultrasound screening. Surveillance of patients with detected AAA. All subjects considered for surgical AAA repair if clinical need.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Prevalence and incidence of AAA in men and women 65 - 80 years of age in community.
Secondary outcome measures
The effect of AAA screening on mortality from AAA and AAA surgical workload.
Overall trial start date
01/01/1989
Overall trial end date
31/12/2015
Reason abandoned
Eligibility
Participant inclusion criteria
Men and women aged 65 - 80 years
Participant type
Patient
Age group
Senior
Gender
Both
Target number of participants
16,000
Participant exclusion criteria
No specific exclusions
Recruitment start date
01/01/1989
Recruitment end date
31/12/2015
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Scott Research Unit
Chichester
PO19 6SE
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)151 794 5900
dot.lambert@dh.gsi.gov.uk
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
Department of Health (UK): 1989 - 1993 (ref: 121/2133)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Funder name
DOH NHS R&D Programme for Cardiovascular Disease and Stroke (UK): 1994 - 1999 (ref: PA1)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Funder name
Charitable donations and 'own account funding' (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
Results in http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17514666
Publication citations
-
Results
Ashton HA, Gao L, Kim LG, Druce PS, Thompson SG, Scott RA, Fifteen-year follow-up of a randomized clinical trial of ultrasonographic screening for abdominal aortic aneurysms., Br J Surg, 2007, 94, 6, 696-701, doi: 10.1002/bjs.5780.