What is the ISRCTN registry?
ISRCTN is a registry and curated database containing the basic set of data items deemed essential to describe a study at inception, as per the requirements set out by the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) and the International Committee of Medical Journal Editors (ICMJE) guidelines. All study records in the database are freely accessible and searchable and have been assigned an ISRCTN ID. The Terms and Conditions enable anyone to cite with attribution the details in each study record, and encourage unrestricted use of all metadata generated during the process of registration, updating or reporting.
The registry was launched in 2000, in response to the growing body of opinion in favour of prospective registration of randomised controlled trials (RCTs). Originally ISRCTN stood for 'International Standard Randomised Controlled Trial Number'; however, over the years the scope of the registry has widened beyond randomised controlled trials to include any study designed to assess the efficacy of health interventions in a human population. This includes both observational and interventional trials.
We work with a number of stakeholders to improve the publicly available information about clinical trials:
- Support open access to clinical trial data information, in line with World Health Organization guidelines, ICMJE statements and Industry recommendations.
- Contribute to the trial registration objectives of key organizations, such as the UK Department of Health and Social Care - via the NIHR Clinical Research Network (CRN) Portfolio, the Wellcome Trust and The Medical Research Council (MRC).
- Collaborate to streamline trial registration processes, with The National Institute for Health Research through the NIHR Portfolio, and the Health Research Authority and its partners through the Integrated Research Application System (IRAS).
- Cooperate with INVOLVE and the Association of Medical Research Charities to ensure that current and future participants are better informed about relevant trials.
- Maximise the visibility of clinical trials data by feeding it into the WHO clinical trial search portal and Be Part of Research (if recruiting in the UK).
The ISRCTN registry has also taken part in the WHO Working Group on Best Practice for Clinical Trials Registers (BPG).
What can I find in a study record?
ISRCTN records include the 24 items defined by the WHO. The record also gives information about:
- Condition category
- Date when the record was last reviewed and corresponding notes
- Participating sites
- Plain English summary if available
- Publication and data sharing plans
- Resulting publications
On this site you can:
- Register your clinical studies and submit and manage your records
- Find and view clinical studies. Differentiate categories at a glance and search by condition, intervention, funder, demographics, etc.
- Download data for further analysis
The ISRCTN registry does not provide patient recruitment services. Users in the UK looking for information on how to take part in a clinical trial, please visit Be Part of Research. For any other country, please contact your medical practitioner.