Contact information
Type
Scientific
Primary contact
Prof Chris Griffiths
ORCID ID
Contact details
Stott Lane
Salford
M6 8HD
United Kingdom
chris.griffiths@srft.nhs.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
7310
Study information
Scientific title
Acronym
Web based cognitive behaviour therapy for people with psoriasis
Study hypothesis
Psoriasis is a chronic inflammatory skin disease affecting approximately 2-3% of the population. The condition is incurable at this stage and the course is recurrent, with periods of remission. It is believed to be a genetic disease, with the genetic tendency thought to be triggered by various environmental factors including infection, skin trauma, certain medications and stress.
Previous research has shown that psoriasis patients have a high incidence of psychological distress, with studies reporting psychological disturbance in the order of 30 - 40% of patients. Psychological distress reported by psoriasis patients includes increased levels of anxiety, depression, excessive worry, reduced quality of life and impaired everyday functioning. Overall, psoriasis patients report more psychological distress than any other dermatology group.
Ethics approval
MREC approved (ref: 08/H1012/17)
Study design
Single centre randomised interventional treatment trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
GP practices
Trial type
Treatment
Patient information sheet
Condition
Topic: Skin; Subtopic: Skin (all Subtopics); Disease: Dermatology
Intervention
Cognitive behaviour therapy (CBT) in a web-based format. This method allows participants to complete the study in privacy, at their own convenience and makes the treatment more broadly accessible.
Follow up length: 6 months
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Subjective reports of self efficacy
Secondary outcome measures
1. Change in illness beliefs
2. Improved quality of life
3. Reduced alcohol consumption
Overall trial start date
01/04/2009
Overall trial end date
31/12/2009
Reason abandoned
Eligibility
Participant inclusion criteria
Male and female, lower age limit of 16 years
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
Planned sample size: 120
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/04/2009
Recruitment end date
31/12/2009
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Stott Lane
Salford
M6 8HD
United Kingdom
Sponsor information
Organisation
Salford Royal NHS Foundation Trust (UK)
Sponsor details
Hope Hospital
Stott Lane
Salford
M6 8HD
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Charity
Funder name
Psoriasis and Psoriatic Arthritis Alliance (PAPAA) (UK)
Alternative name(s)
PAPAA
Funding Body Type
private sector organisation
Funding Body Subtype
other non-profit
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2013 results in http://www.ncbi.nlm.nih.gov/pubmed/23551271
Publication citations
-
Results
Bundy C, Pinder B, Bucci S, Reeves D, Griffiths CE, Tarrier N, A novel, web-based, psychological intervention for people with psoriasis: the electronic Targeted Intervention for Psoriasis (eTIPs) study., Br. J. Dermatol., 2013, 169, 2, 329-336, doi: 10.1111/bjd.12350.