The effects of propofol and sevoflurane on electrocardiogram (ECG) indices of transmural dispersion of repolarisation in children

ISRCTN ISRCTN04254583
DOI https://doi.org/10.1186/ISRCTN04254583
Secondary identifying numbers N0206121784
Submission date
12/09/2003
Registration date
12/09/2003
Last edited
30/04/2015
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr S Whyte
Scientific

Institute of Child Health
Royal Liverpool Children's Hospital NHS Trust
Alder Hey
Eaton Road
Liverpool
L12 2AP
United Kingdom

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Hospital
Study typeTreatment
Scientific titleThe effects of propofol and sevoflurane on electrocardiogram (ECG) indices of transmural dispersion of repolarisation in children
Study objectivesDo the anaesthetics drugs propofol and sevoflurane affect surface electrocardiogram (ECG) indices of transmural dispersion of repolarisation?
Ethics approval(s)Not provided at time of registration
Health condition(s) or problem(s) studiedSurgery: Anaesthesia
InterventionPatients will be randomised to receive either propofol or sevoflurane at induction of anaesthesia.
Intervention typeDrug
Pharmaceutical study type(s)
PhaseNot Applicable
Drug / device / biological / vaccine name(s)Propofol, sevoflurane
Primary outcome measureChange in T wave interval peak to end. Change in T wave interval peak to end/onset Q and T wave peak.
Secondary outcome measuresNot provided at time of registration
Overall study start date01/01/2003
Completion date01/06/2003

Eligibility

Participant type(s)Patient
Age groupChild
Lower age limit1 Year
Upper age limit12 Years
SexBoth
Target number of participantsNot provided at time of registration
Key inclusion criteriaAmerican Society of Anesthesiologists (ASA) I and II infants and children aged >1 and <12 years undergoing elective surgery.
Key exclusion criteriaNot provided at time of registration
Date of first enrolment01/01/2003
Date of final enrolment01/06/2003

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

Institute of Child Health
Liverpool
L12 2AP
United Kingdom

Sponsor information

Department of Health (UK)
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website http://www.doh.gov.uk

Funders

Funder type

Government

Royal Liverpool Children's NHS Trust (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan