The effects of propofol and sevoflurane on electrocardiogram (ECG) indices of transmural dispersion of repolarisation in children
| ISRCTN | ISRCTN04254583 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN04254583 |
| Secondary identifying numbers | N0206121784 |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 30/04/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr S Whyte
Scientific
Scientific
Institute of Child Health
Royal Liverpool Children's Hospital NHS Trust
Alder Hey
Eaton Road
Liverpool
L12 2AP
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | The effects of propofol and sevoflurane on electrocardiogram (ECG) indices of transmural dispersion of repolarisation in children |
| Study objectives | Do the anaesthetics drugs propofol and sevoflurane affect surface electrocardiogram (ECG) indices of transmural dispersion of repolarisation? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Anaesthesia |
| Intervention | Patients will be randomised to receive either propofol or sevoflurane at induction of anaesthesia. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Propofol, sevoflurane |
| Primary outcome measure | Change in T wave interval peak to end. Change in T wave interval peak to end/onset Q and T wave peak. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/01/2003 |
| Completion date | 01/06/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Child |
| Lower age limit | 1 Year |
| Upper age limit | 12 Years |
| Sex | Both |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | American Society of Anesthesiologists (ASA) I and II infants and children aged >1 and <12 years undergoing elective surgery. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/2003 |
| Date of final enrolment | 01/06/2003 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Institute of Child Health
Liverpool
L12 2AP
United Kingdom
L12 2AP
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.doh.gov.uk |
|---|
Funders
Funder type
Government
Royal Liverpool Children's NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
