Contact information
Type
Scientific
Primary contact
Dr Bernadette Ewah
ORCID ID
Contact details
Epsom and St Helier NHS Trust
Epsom General Hospital
Dorking Road
Epsom
Surrey
KT18 7EG
United Kingdom
+44 (0)1372 7355270
bewah99@yahoo.com
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0112112997
Study information
Scientific title
Tidal Volume - Cytokine levels trial in anaesthetised patients undergoing positive pressure ventilation
Acronym
Study hypothesis
What tidal volume is beneficial for artificial ventilation during surgery?
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Surgery: Ventilation
Intervention
Patients randomly divided into two groups. One group is ventilated with a standard tidal volume of 10 ml/kg. The second group is ventilated with 6 ml/kg. Cytokine levels in bronchial aspirate and blood are measured.
Intervention type
Procedure/Surgery
Phase
Not Specified
Drug names
Primary outcome measures
Cytokine levels.
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/02/2002
Overall trial end date
01/02/2004
Reason abandoned
Eligibility
Participant inclusion criteria
Not provided at time of registration
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
50
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/02/2002
Recruitment end date
01/02/2004
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Epsom and St Helier NHS Trust
Surrey
KT18 7EG
United Kingdom
Sponsor information
Organisation
Department of Health
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
Epsom and St Helier University Hospitals NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary