Condition category
Not Applicable
Date applied
11/02/2003
Date assigned
11/02/2003
Last edited
07/09/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Richard Holland

ORCID ID

Contact details

School of Medicine
Health Policy & Practice
University of East Anglia
Norfolk
Norwich
NR4 7TJ
United Kingdom
+44 (0)1603 593574
r.holland@uea.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

G106/991

Study information

Scientific title

Acronym

The HOMER trial

Study hypothesis

To determine whether domiciliary medication review leads to reductions in emergency hospital admissions and an improvement in quality of life compared to standard care among elderly subjects (80 years old and over).

Ethics approval

Not provided at time of registration.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Quality of life

Patient information sheet

Condition

Not Applicable

Intervention

Two groups:

Control group received standard care (whatever that entails).

Intervention group are referred to a review pharmacist. The review pharmacist will complete a standard medication review form and will then arrange a home visit at a time when they can meet the patient and any carers helping them with their drugs. The home visit will include a brief assessment of their ability to self-medicate and an assessment of drug compliance. The review pharmacist will, where appropriate:
a. Educate the patient/carer
b. Remove out-of-date drugs (with the patient's consent)
c. Feedback to the GP possible drug reactions/interactions
d. Feedback to the local pharmacist the need for a compliance aid.

One follow-up visit will occur at 6-8 weeks post-recruitment to allow reinforcement of the original advice.

Intervention type

Other

Phase

Not Applicable

Drug names

Primary outcome measures

Total number of emergency hospital admissions by 6-months

Secondary outcome measures

1. Total number of emergency hospital admissions by 3 months
2. Hospital/nursing/residential home admissions for respite care by 3 & 6 months
3. Admissions to nursing/residential care for long-term care by 3 & 6 months
4. Deaths by 3 & 6 months
5. Self-assessed quality of life at 3 & 6 months (using EQ-5D)
6. Average medication costs at 6 months

Overall trial start date

01/01/2001

Overall trial end date

31/12/2004

Reason abandoned

Eligibility

Participant inclusion criteria

1. Discharged after an emergency hospital admission
2. 80 years and over
3. Prescribed two or more daily medications
4. Living in own home or warden controlled accommodation
5. Norfolk or Suffolk resident

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

850

Participant exclusion criteria

Living in a residential or nursing home.

Recruitment start date

01/01/2001

Recruitment end date

31/12/2004

Locations

Countries of recruitment

United Kingdom

Trial participating centre

School of Medicine
Norwich
NR4 7TJ
United Kingdom

Sponsor information

Organisation

Medical Research Council (MRC) (UK)

Sponsor details

20 Park Crescent
London
W1B 1AL
United Kingdom
+44 20 7636 5422
clinical.trial@headoffice.mrc.ac.uk

Sponsor type

Research council

Website

http://www.mrc.ac.uk

Funders

Funder type

Research council

Funder name

NHS Eastern Region R&D (reference number: HSR/1199/2) (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Medical Research Council (reference number: G106/991) (UK)

Alternative name(s)

MRC

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

United Kingdom

Funder name

Norfolk Health Authority (no reference number allocated) (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Norfolk Social Services (no reference number allocated) (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Suffolk Social Services (no reference number allocated) (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

Pharmacy Practice Unit, UEA (no reference number allocated) (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2005 results in http://www.ncbi.nlm.nih.gov/pubmed/15665005

Publication citations

  1. Results

    Holland R, Lenaghan E, Harvey I, Smith R, Shepstone L, Lipp A, Christou M, Evans D, Hand C, Does home based medication review keep older people out of hospital? The HOMER randomised controlled trial., BMJ, 2005, 330, 7486, 293, doi: 10.1136/bmj.38338.674583.AE.

Additional files

Editorial Notes