Randomised controlled trial and economic evaluation of domiciliary medication review by pharmacists in Norfolk & Suffolk
| ISRCTN | ISRCTN06813178 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN06813178 |
| Secondary identifying numbers | G106/991 |
- Submission date
- 11/02/2003
- Registration date
- 11/02/2003
- Last edited
- 07/09/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Other
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Richard Holland
Scientific
Scientific
School of Medicine
Health Policy & Practice
University of East Anglia
Norfolk
Norwich
NR4 7TJ
United Kingdom
| Phone | +44 (0)1603 593574 |
|---|---|
| r.holland@uea.ac.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Quality of life |
| Scientific title | |
| Study acronym | The HOMER trial |
| Study objectives | To determine whether domiciliary medication review leads to reductions in emergency hospital admissions and an improvement in quality of life compared to standard care among elderly subjects (80 years old and over). |
| Ethics approval(s) | Not provided at time of registration. |
| Health condition(s) or problem(s) studied | Not Applicable |
| Intervention | Two groups: Control group received standard care (whatever that entails). Intervention group are referred to a review pharmacist. The review pharmacist will complete a standard medication review form and will then arrange a home visit at a time when they can meet the patient and any carers helping them with their drugs. The home visit will include a brief assessment of their ability to self-medicate and an assessment of drug compliance. The review pharmacist will, where appropriate: a. Educate the patient/carer b. Remove out-of-date drugs (with the patient's consent) c. Feedback to the GP possible drug reactions/interactions d. Feedback to the local pharmacist the need for a compliance aid. One follow-up visit will occur at 6-8 weeks post-recruitment to allow reinforcement of the original advice. |
| Intervention type | Other |
| Primary outcome measure | Total number of emergency hospital admissions by 6-months |
| Secondary outcome measures | 1. Total number of emergency hospital admissions by 3 months 2. Hospital/nursing/residential home admissions for respite care by 3 & 6 months 3. Admissions to nursing/residential care for long-term care by 3 & 6 months 4. Deaths by 3 & 6 months 5. Self-assessed quality of life at 3 & 6 months (using EQ-5D) 6. Average medication costs at 6 months |
| Overall study start date | 01/01/2001 |
| Completion date | 31/12/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Senior |
| Sex | Both |
| Target number of participants | 850 |
| Key inclusion criteria | 1. Discharged after an emergency hospital admission 2. 80 years and over 3. Prescribed two or more daily medications 4. Living in own home or warden controlled accommodation 5. Norfolk or Suffolk resident |
| Key exclusion criteria | Living in a residential or nursing home. |
| Date of first enrolment | 01/01/2001 |
| Date of final enrolment | 31/12/2004 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
School of Medicine
Norwich
NR4 7TJ
United Kingdom
NR4 7TJ
United Kingdom
Sponsor information
Medical Research Council (MRC) (UK)
Research council
Research council
20 Park Crescent
London
W1B 1AL
United Kingdom
| Phone | +44 (0)20 7636 5422 |
|---|---|
| clinical.trial@headoffice.mrc.ac.uk | |
| Website | http://www.mrc.ac.uk |
Funders
Funder type
Research council
NHS Eastern Region R&D (reference number: HSR/1199/2) (UK)
No information available
Medical Research Council (reference number: G106/991) (UK)
Government organisation / National government
Government organisation / National government
- Alternative name(s)
- Medical Research Council (United Kingdom), UK Medical Research Council, MRC
- Location
- United Kingdom
Norfolk Health Authority (no reference number allocated) (UK)
No information available
Norfolk Social Services (no reference number allocated) (UK)
No information available
Suffolk Social Services (no reference number allocated) (UK)
No information available
Pharmacy Practice Unit, UEA (no reference number allocated) (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 05/02/2005 | Yes | No |
