The effectiveness and cost-effectiveness of public access defibrillation in urban and rural populations in Northern Ireland

ISRCTN	ISRCTN07286796
DOI	https://doi.org/10.1186/ISRCTN07286796
Secondary identifying numbers	COM/2371/03

Submission date: 20/01/2006
Registration date: 30/01/2006
Last edited: 18/03/2008

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Study website

Contact information

Prof Frank Kee
Scientific

QUB Centre For Clinical and Population Science
1st Floor Mulhouse building
Royal Victoria Hospital
Grosvenor road
Belfast
BT12 6BA
United Kingdom

Phone	+44 (0)28 90632746
Email	f.kee@qub.ac.uk

Study information

Study design	An observational study for one year followed by an intervention using public access defibrillation on the cohort
Primary study design	Interventional
Secondary study design	Cohort study
Study setting(s)	Not specified
Study type	Prevention
Scientific title
Study acronym	Northern Ireland Public Access Defibrillation (NIPAD)
Study objectives	Training laypersons such as first responders and police officers to carry and use automated external defibrillators to attend the scene of out-of-hospital sudden cardiac arrests will result in the resuscitation of additional patients by a reduction in the response time compared to the existing emergency medical service response.
Ethics approval(s)	Ethics approval received from the Northern Ireland Research Ethics Committee on the 26th March 2003 (ref: 47/03).
Health condition(s) or problem(s) studied	Out-of-hospital sudden cardiac arrest
Intervention	Training lay cardiac first responders and police officers to carry and use automated external defibrillators in response to sudden out-of-hospital cardiac arrest in fixed and mobile locations.
Intervention type	Other
Primary outcome measure	1. Survival after hospital discharge following out-of-hospital sudden cardiac arrest 2. Cost-effectiveness of public access defibrillation in the study areas
Secondary outcome measures	1. Reduction in response time compared to existing emergency medical services 2. Return of spontaneous circulation 3. The modelling of the results to Northern Ireland as a whole using a spatial modelling approach 4. The modelling of the effectiveness and cost-effectiveness of public access defibrillation across Northern Ireland
Overall study start date	01/01/2004
Completion date	03/04/2006

Eligibility

Participant type(s)	Patient
Age group	Adult
Sex	Both
Target number of participants	300,000 people in study area, expected 300 cardiac arrests
Key inclusion criteria	All patients with a presumed out-of-hospital sudden cardiac arrest over the age of 14 in Antrim, Ballymena, Magherafelt and North and West Belfast district council areas of Northern Ireland.
Key exclusion criteria	Out-of-hospital sudden deaths due to non-cardiac causes including trauma, drowning, overdose, poisoning and fire.
Date of first enrolment	01/01/2004
Date of final enrolment	03/04/2006

Locations

Countries of recruitment

Northern Ireland
United Kingdom

Study participating centre

QUB Centre For Clinical and Population Science

Belfast
BT12 6BA
United Kingdom

Sponsor information

The Research and Development Office for Health and Personal Social Services in Northern Ireland (UK)
Government

R&D Office
12-22 Linenhall street
Belfast
BT2 8BS
United Kingdom

Phone	+44 (0)28 90553617
Email	joanne.O'Neill@rdo.n-i.nhs.uk
Website	http://www.centralservicesagency.n-i.nhs.uk/display
"ROR"	https://ror.org/02tdmfk69

Funders

Funder type

Government

The Research and Development Office for Health and Personal Social Services in Northern Ireland (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	Results	01/03/2008		Yes	No