A pregnancy intervention to reduce postprandial glucose excursions in the primary prevention of paediatric obesity

ISRCTN ISRCTN10344179
DOI https://doi.org/10.1186/ISRCTN10344179
Secondary identifying numbers NHMRC Project Grant 512363
Submission date
18/01/2007
Registration date
09/02/2007
Last edited
27/09/2017
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Pregnancy and Childbirth
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Jennie Brand-Miller
Scientific

Human Nutrition Unit
University of Sydney
NSW 2006
Sydney
2006
Australia

Email j.brandmiller@mmb.usyd.edu.au

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Other
Study typePrevention
Scientific titleA pregnancy intervention to reduce postprandial glucose excursions in the primary prevention of paediatric obesity: a randomised controlled trial
Study acronymCHOPP (Childhood Obesity Primary Prevention Study)
Study objectivesA diet designed to reduce maternal blood glucose levels will reduce the prevalence of large gestational age and childhood obesity.
Ethics approval(s)To be submitted to the University of Sydney Human Ethics Committee and relevant teaching hospitals
Health condition(s) or problem(s) studiedPregnancy, obesity
InterventionA conventional healthy diet or a low glycaemic index diet from 12 to 16 weeks gestation for the remainder of pregnancy.
Intervention typeOther
Primary outcome measure1. Prevalence of large gestational age at birth (more than 90th centile)
2. Prevalence of childhood obesity as determined by BMI
Secondary outcome measures1. Prevalence of gestational diabetes
2. Ponderal index
3. Prevalence of 'small for gestational age'
Overall study start date01/01/2008
Completion date31/12/2012

Eligibility

Participant type(s)Patient
Age groupAdult
SexFemale
Target number of participants1650
Key inclusion criteriaHealthy pregnant women at 12 to 16 weeks gestation who agree to be randomised
Key exclusion criteria1. Women with pre-gestational diabetes
2. Multiple birth
3. Assisted reproduction
4. Special diet or referred to a dietitian for other reasons
Date of first enrolment01/01/2008
Date of final enrolment31/12/2012

Locations

Countries of recruitment

  • Australia

Study participating centre

Human Nutrition Unit
Sydney
2006
Australia

Sponsor information

National Health and Medical Research Council (Australia)
Government

GPO Box 1421
Canberra
2601
Australia

Email grantnet.help@nhmrc.gov.au
Website http://www.nhmrc.gov.au/
ROR logo "ROR" https://ror.org/011kf5r70

Funders

Funder type

Government

National Health and Medical Research Council (NHMRC) (Australia): application for project grant in 2007 for funding in 2008

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/10/2006 Yes No

Editorial Notes

27/09/2017: internal review.