Contact information
Type
Scientific
Primary contact
Dr Lee Shepstone
ORCID ID
Contact details
School of Medicine
Health
Policy & Practice
University of East Anglia
Norwich
NR4 7TJ
United Kingdom
+44 (0)1603 592100
L.Shepstone@uea.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
16039
Study information
Scientific title
A pragmatic randomised clinical trial of the effectiveness and cost effectiveness of targeted population screening for low bone mineral density (BMD) in the prevention of neck of femur fractures
Acronym
SCOOP - SCreening for Osteoporosis in Older Persons
Study hypothesis
Screening for women aged 70-85 at high risk of osteoporotic fracture with appropriate treatment will reduce the incidence fractures
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Screening
Patient information sheet
Condition
Prevention of osteoporotic/fragility fractures
Intervention
Intervention is screening for high risk of fracture based upon self-reported risk factors and BMD measurements in some subjects. Those deemed to be at high risk will be recommended to their GP for appropriate treatment.
Those in the control group will receive lifestyle advice only.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
All fractures (excluding those of hands, feet, nose and skull), ascertained by self report and separately by interrogation of hospital accident and emergency (A&E), radiology and admissions systems in hospitals serving the identified populations.
Secondary outcome measures
Quality of Life, Mortality
Overall trial start date
01/01/2005
Overall trial end date
31/12/2010
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Female, aged 70-85, resident in the study areas
Participant type
Patient
Age group
Senior
Gender
Female
Target number of participants
800
Participant exclusion criteria
1. Already on treatment for osteoporosis (other than Vitamin D and Calcium)
2. Unable to provide informed consent
Recruitment start date
01/01/2005
Recruitment end date
31/12/2010
Locations
Countries of recruitment
United Kingdom
Trial participating centre
School of Medicine, Health, Policy & Practice
Norwich
NR4 7TJ
United Kingdom
Funders
Funder type
Charity
Funder name
Arthritis Research Campaign 16039 (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
1. 2012 protocol in http://www.ncbi.nlm.nih.gov/pubmed/22314936
2. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29254858
Publication citations
-
Protocol
Shepstone L, Fordham R, Lenaghan E, Harvey I, Cooper C, Gittoes N, Heawood A, Peters T, O'Neill T, Torgerson D, Holland R, Howe A, Marshall T, Kanis J, McCloskey E, A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: rationale, design and methods for the SCOOP study., Osteoporos Int, 2012, 23, 10, 2507-2515, doi: 10.1007/s00198-011-1876-7.