Low-dose doxycycline in the treatment of periodontitis in smokers

ISRCTN ISRCTN11033714
DOI https://doi.org/10.1186/ISRCTN11033714
Secondary identifying numbers N/A
Submission date
15/10/2002
Registration date
15/10/2002
Last edited
24/11/2010
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Other
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Ian Needleman
Scientific

Department of Periodontology
Eastman Dental Institute for Oral Health Care Sciences
University College London
256 Gray's Inn Road
London
WC1X 8LD
United Kingdom

Phone +44 (0) 20 7915 2340
Email i.needleman@eastman.ucl.ac.uk

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Not specified
Study typeNot Specified
Scientific title
Study objectivesNot provided at time of registration.
Ethics approval(s)Not provided at time of registration.
Health condition(s) or problem(s) studiedPeriodontology
Intervention1. Non-surgical periodontal therapy plus twice daily 20 mg doxycycline for 3 months
2. Non-surgical periodontal therapy plus twice daily placebo for 3 months
Intervention typeOther
Primary outcome measureNot provided at time of registration.
Secondary outcome measuresNot provided at time of registration.
Overall study start date15/10/2000
Completion date15/10/2005

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexNot Specified
Target number of participantsNot provided at time of registration.
Key inclusion criteria1. Smokers unable to quit
2. Moderate-severe chronic periodontitis
3. Age 30-70
Key exclusion criteriaNot provided at time of registration.
Date of first enrolment15/10/2000
Date of final enrolment15/10/2005

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

Department of Periodontology
London
WC1X 8LD
United Kingdom

Sponsor information

CollaGenex Pharmaceuticals Inc. (USA)
Industry

41 University Drive
Newtown
PA 18940
United States of America

Website http://www.collagenex.com
ROR logo "ROR" https://ror.org/01rdxvn05

Funders

Funder type

Industry

Mainly self-supported: design, conduct, analysis and reporting are independent of industry. Biochemical analyses funded by CollaGenex Inc.

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/04/2007 Yes No