Condition category
Not Applicable
Date applied
15/10/2002
Date assigned
15/10/2002
Last edited
24/11/2010
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Ian Needleman

ORCID ID

Contact details

Department of Periodontology
Eastman Dental Institute for Oral Health Care Sciences
University College London
256 Gray's Inn Road
London
WC1X 8LD
United Kingdom
+44 (0) 20 7915 2340
i.needleman@eastman.ucl.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

Study hypothesis

Not provided at time of registration.

Ethics approval

Not provided at time of registration.

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Periodontology

Intervention

1. Non-surgical periodontal therapy plus twice daily 20 mg doxycycline for 3 months
2. Non-surgical periodontal therapy plus twice daily placebo for 3 months

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Not provided at time of registration.

Secondary outcome measures

Not provided at time of registration.

Overall trial start date

15/10/2000

Overall trial end date

15/10/2005

Reason abandoned

Eligibility

Participant inclusion criteria

1. Smokers unable to quit
2. Moderate-severe chronic periodontitis
3. Age 30-70

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

Not provided at time of registration.

Participant exclusion criteria

Not provided at time of registration.

Recruitment start date

15/10/2000

Recruitment end date

15/10/2005

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Department of Periodontology
London
WC1X 8LD
United Kingdom

Sponsor information

Organisation

CollaGenex Pharmaceuticals Inc. (USA)

Sponsor details

41 University Drive
Newtown
PA 18940
United States of America

Sponsor type

Industry

Website

http://www.collagenex.com

Funders

Funder type

Industry

Funder name

Mainly self-supported: design, conduct, analysis and reporting are independent of industry. Biochemical analyses funded by CollaGenex Inc.

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2007 results in http://www.ncbi.nlm.nih.gov/pubmed/17324155

Publication citations

  1. Results

    Needleman I, Suvan J, Gilthorpe MS, Tucker R, St George G, Giannobile W, Tonetti M, Jarvis M, A randomized-controlled trial of low-dose doxycycline for periodontitis in smokers., J. Clin. Periodontol., 2007, 34, 4, 325-333, doi: 10.1111/j.1600-051X.2007.01058.x.

Additional files

Editorial Notes