Plain English Summary
Background and study aims
Resistance training describes a type of training where you move against a force that resists your movement. Krill Oil is a supplement that could be helpful to those who are doing resistance training.
The aim of this study is to investigate the effect of a nutritional intervention, Krill Oil, in combination with resistance training on muscular health in healthy participants.
Who can participate?
Males aged 18 to 30 years old who are currently doing resistance training at least two times per week for the past six months.
What does the study involve?
Participants undergo a resistance training program (programmed, non-linear training split) four days per week for a period of 8 weeks. Participants are randomly allocated to one of two groups. Those in the first group receive 3grams of a placebo (a dummy capsule) that contains safflower oil. Those in the second group receive the Krill oil (3 grams) capsule. Supplements are consumed prior to workouts on training days while eating breakfast on non-training days. Participants are assessed for their body composition and muscle strength after eight weeks.
What are the possible benefits and risks of participating?
Participants may benefit from an increase in lean body mass and strength. Participation in exercise includes the potential risk of injury.
Where is the study run from?
Applied Science and Performance Institute (USA)
When is the study starting and how long is it expected to run for?
January 2016 to December 2016
Who is funding the study?
Rimfrost USA (USA)
Who is the main contact?
Dr Jacob Wilson
The effects of krill oil supplementation combined with resistance training on body composition and athletic performance
The aim of this study is to investigate the ability of Krill Oil to augment resistance training-induced changes in body composition and performance.
IntegReview IRB, Austin, TX, 14/03/2016, ref: Protocol Number: 7952
Single-center randomised double-blind placebo-controlled parallel interventional study
Primary study design
Secondary study design
Randomised parallel trial
Quality of life
Patient information sheet
No participant information sheet available.
Participants undergo a resistance training program (programmed, non-linear training split) four days per week for a period of 8 weeks.
Participants are allocated to one of two groups. Those in the first group receive 3 grams of Placebo (safflower oil) in a softgel 6500 mg capsule. Those in the second group receive 3 grams of Krill (Euphausia superba) Oil (Rimfrost Sublime, Rimfrost USA LLC, Merry Hill, NC, USA, Lot 8723-15-01-03), administered as 6 500mg softgel capsules.
Supplements are consumed pre-workout on training days, and with breakfast on non-training days.
Participants are followed up for their body composition using the whole-body Dual-Energy X-ray Absorptiometry (DXA) at baseline and 8 weeks. Participants are assessed for their strength using one repetition maximum (1RM) on a bench press and leg press at baseline and 8 weeks.
Primary outcome measure
1. Body composition is measured using the whole-body Dual-Energy X-ray Absorptiometry (DXA) at baseline and 8 weeks
2. Strength is measured using one repetition maximum (1RM) on a bench press and leg press at baseline and 8 weeks
Secondary outcome measures
1. Perceptual Measures is measured using perceived recovery at beginning and end of every week
2. Cognition is measured using a Stroop Test at baseline and eight weeks
3. Safety is measured using comprehensive metabolic panel (CMP) at baseline and eight weeks
4. Complete blood count (CBC) and lipid panels is measured using blood tests at baseline and eight weeks
Overall trial start date
Overall trial end date
Reason abandoned (if study stopped)
Participant inclusion criteria
1. Males 18 to 30 years of age
2. Resistance training at least 2 times per week for the past six months
3. Minimum of 1 year of training experience active
4. Currently resistance training
Target number of participants
Participant exclusion criteria
1. Free of musculoskeletal, metabolic, and respiratory disorders
2. Free of cardiovascular disease
3. No musculoskeletal injuries with the last six months
4. No history of smoking or drug use
5. No history of excessive alcohol consumption
6. Not taking prescription medication
7. Have not used a fish oil-, thermogenic-, protein-, amino acid-, or creatine supplement within the prior two months
8. Have not habitually used caffeine (e.g. more than 2 cups of coffee per day)
Recruitment start date
Recruitment end date
Countries of recruitment
United States of America
Trial participating centre
Applied Science and Performance Institute
United States of America
Funding Body Type
Funding Body Subtype
Results and Publications
Publication and dissemination plan
Planned publication in a high-impact peer reviewed journal.
IPD sharing statement:
The datasets generated during and/or analysed during the current study are/will be available upon request from Dr Jacob M Wilson, email@example.com.
Intention to publish date
Participant level data
Available on request
Basic results (scientific)
2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/29854443