Plain English Summary
Background and study aims
Omitted medication doses, that is prescribed medicine that has not been given to a patient at the time that their next dose is due, are commonly seen in UK hospitals. These omitted doses can and do lead to harm for patients, particularly if medicines involved are ‘critical’ in that they require timely and regular administration to be effective, such as antibiotics and drugs to treat epilepsy. The aim of this study is to find out whether introducing a pharmacy technician to support nurse drug administration rounds in a NHS hospital in England can reduce the number of omitted doses when compared to wards where this technician support is not provided.
Who can participate?
Registered pharmacy technicians, medical staff and nursing stuff working in participating hospital wards.
What does the study involve?
Four pairs of medical, surgical and/or specialty wards are randomly selected to take part, and one ward within each pair is randomly selected to receive pharmacy technician support. The study hospital uses electronic recording of prescribing and drug administration, and the data used to compare the number of omitted doses and number of doses due to be given to patients on the wards. Trained pharmacy technicians visit the chosen wards on weekdays over 1 month to help them administer and document drug administration. The proportion of omitted doses as well as dose omissions involving ‘critical’ medicines are then compared between the wards with technician support and those without to see if they are reduced. Pharmacy staff, medical staff and nurses involved in the study are also asked their views on how well they think the added support works and if they can suggest any improvements to support possible wider roll-out in the future.
What are the possible benefits and risks of participating?
Whilst there are no direct benefits to health care staff who participate in this study, they may be given the opportunity to reflect on their own practice to identify new ways to work more closely with other health care professionals to deliver integrated patient care.
Where is the study run from?
Salford Royal NHS Foundation Trust (UK)
When is the study starting and how long is it expected to run for?
October 2015 to September 2016
Who is funding the study?
United Kingdom Clinical Pharmacy Association (UKCPA) and Pharmacy Research UK (PRUK)
Who is the main contact?
Dr Richard Keers
Trial website
Contact information
Type
Scientific
Primary contact
Dr Richard Keers
ORCID ID
http://orcid.org/0000-0001-7854-8154
Contact details
Room 1.185
Stopford Building
Manchester Pharmacy School
Oxford Road
The University of Manchester
Manchester
M13 9PL
United Kingdom
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
2
Study information
Scientific title
Evaluation of pharmacy TECHnician supported MEDication administration rounds (TECHMED) on reducing omitted doses: a randomised controlled trial and process evaluation in a university teaching hospital.
Acronym
TECHMED
Study hypothesis
The aim of this research study is to conduct a randomised controlled trial (RCT) to evaluate the effect of introducing pharmacy TECHnician supported MEDication administration rounds (TECHMED) to reduce the frequency of omitted doses at a NHS hospital in England.
Ethics approval
The University of Manchester: University Research Ethics Committee 2, 26/11/2015, ref: 1550
Study design
Single-centre randomised controlled trial.
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Other
Patient information sheet
Not available in web format, please use contact details to request a participant information sheet
Condition
Omitted doses of medications occurring on inpatient hospital wards.
Intervention
This randomised controlled trial involves a control and intervention arm and will be divided into three phases – pre-intervention/baseline, intervention (where intervention wards receive the TECHMED intervention but the control wards do not) and post-intervention. The pre- and post-intervention phases will involve no TECHMED support on the intervention or control wards, and will last 1 month with the intervention phase also lasting 1 month.
Trained pharmacy technicians already employed by the study hospital will perform the TECHMED intervention. These trained technicians will accompany nursing staff on medication administration rounds on weekdays during a 1 month intervention period.
During the medicines administration rounds, pharmacy technicians will accompany nurses and directly support them during this process, helping to source medications and solve medicines administration challenges to promote timely and safe administration of medicines.
Intervention type
Other
Phase
Drug names
Primary outcome measures
Rate of all omitted doses, measured using extracted prescribing and medicines administration data from electronic inpatient record systems at the study hospital. Data will be extracted following completion of each 1 month phase of the study.
Secondary outcome measures
1. Rate of preventable omitted doses (PrOD)
2. Rate of all omitted doses of critical list medications
3. Rate of preventable omitted doses of critical list medications
Overall trial start date
01/10/2015
Overall trial end date
30/09/2016
Reason abandoned
Eligibility
Participant inclusion criteria
Techmed RCT:
1. AFC Band 4/5 professionally registered pharmacy technicians employed by the study hospital who were interested in delivering the TECHMED service and who have drug accuracy checking qualifications and experience of ward work
2. Wards with similar characteristics suitable for randomisation who are interested in taking part, with senior nursing and individual ward manager approval
3. All regular and stat scheduled doses of medication to be given via any route of administration on the chosen study wards.
Process evaluation:
1. AFC Band 4/5 pharmacy technicians responsible for delivering TECHMED services
2. Professionally registered nursing staff of any grade employed by hospital site predominantly on the intervention wards who work directly with TECHMED pharmacy technicians to deliver the service
3. Professionally registered medical, nursing and pharmacy staff of any grade/level of experience employed on the intervention ward(s) who have experienced indirect contact with TECHMED components (e.g. dispensary staff receiving new orders from TECHMED technicians, ward based nursing/medical/pharmacy staff who respond to queries raised by the technicians/nurses)
Participant type
Health professional
Age group
Adult
Gender
Both
Target number of participants
20-30 for process evaluation interviews, 12 technicians to deliver TECHMED intervention
Participant exclusion criteria
Techmed RCT:
1. Inpatient wards which cannot be paired and therefore pooled in the randomisation sampling process (e.g. single units with no similar ward like intensive care, medical admissions)
2. Outpatient environments within study hospital
3. Any inpatient wards which do not utilise electronic prescribing and drug administration systems
4. Pharmacy technicians who are not AFC pay scale band 4/5 or not employed by study hospital
5. Pharmacy technicians without drug accuracy checking qualifications and prior experience of ward work
6. Pharmacy technicians not professionally registered with General Pharmaceutical Council (GPhC)
7. When required PRN doses of medication on the study wards
Process evaluation:
1. Staff not employed on the intervention ward(s)
2. University students (e.g. nursing students)
3. Patients and their relatives/friends/representatives
4. Health care support staff such as physiotherapists, dieticians, SALT, social workers, ward clerks, support workers, occupational therapists, phlebotomists (i.e. not pharmacy/nursing/medical)
Recruitment start date
01/12/2015
Recruitment end date
31/05/2016
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Salford Royal NHS Foundation Trust
Stott Lane
Salford
M6 8HD
United Kingdom
Funders
Funder type
Not defined
Funder name
United Kingdom Clinical Pharmacy Association (UKCPA) and Pharmacy Research UK (PRUK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
1. Planned publication of at least two open access articles relating to this project
2. Planned presentation of findings in at least 2 abstracts at academic/professional conferences during the 2017 season
Intention to publish date
31/12/2017
Participant level data
Not expected to be available
Results - basic reporting
Publication summary