Evaluation of hepatic tissue carbon dioxide as a marker of a liver function and the effort of the Pringle manoeuvre in liver resection.
| ISRCTN | ISRCTN11700554 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN11700554 |
| Secondary identifying numbers | N0192122289 |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 07/09/2012
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr AJ Brooks
Scientific
Scientific
Department of Surgery
E Floor West Block
University Hospital
Nottingham
NG7 2UH
United Kingdom
| Phone | +44 (0)115 9249924 |
|---|---|
| adambrooks@btopenworld.com |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | Is tissue carbon dioxide a valuable marker of liver cell function during liver resection surgery? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Liver resection |
| Intervention | 1. Hyperventilated to a preclamp end tidal CO2 of 3.5 kPa and the clamp will be applied until the tissue CO2 is 10 kPa (approx 10 min) 2. Standard practice |
| Intervention type | Procedure/Surgery |
| Primary outcome measure | Comparison of tissue carbon dioxide and indocyanine green clearance. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/09/2002 |
| Completion date | 31/08/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 20 |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/09/2002 |
| Date of final enrolment | 31/08/2003 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Department of Surgery
Nottingham
NG7 2UH
United Kingdom
NG7 2UH
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.doh.gov.uk |
|---|
Funders
Funder type
Government
Queen's Medical Centre University Hospital NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/08/2007 | Yes | No |
