Evaluation of hepatic tissue carbon dioxide as a marker of a liver function and the effort of the Pringle manoeuvre in liver resection.

ISRCTN ISRCTN11700554
DOI https://doi.org/10.1186/ISRCTN11700554
Secondary identifying numbers N0192122289
Submission date
12/09/2003
Registration date
12/09/2003
Last edited
07/09/2012
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Mr AJ Brooks
Scientific

Department of Surgery
E Floor West Block
University Hospital
Nottingham
NG7 2UH
United Kingdom

Phone +44 (0)115 9249924
Email adambrooks@btopenworld.com

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Not specified
Study typeNot Specified
Scientific title
Study objectivesIs tissue carbon dioxide a valuable marker of liver cell function during liver resection surgery?
Ethics approval(s)Not provided at time of registration
Health condition(s) or problem(s) studiedSurgery: Liver resection
Intervention1. Hyperventilated to a preclamp end tidal CO2 of 3.5 kPa and the clamp will be applied until the tissue CO2 is 10 kPa (approx 10 min)
2. Standard practice
Intervention typeProcedure/Surgery
Primary outcome measureComparison of tissue carbon dioxide and indocyanine green clearance.
Secondary outcome measuresNot provided at time of registration
Overall study start date01/09/2002
Completion date31/08/2003

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexNot Specified
Target number of participants20
Key inclusion criteriaNot provided at time of registration
Key exclusion criteriaNot provided at time of registration
Date of first enrolment01/09/2002
Date of final enrolment31/08/2003

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

Department of Surgery
Nottingham
NG7 2UH
United Kingdom

Sponsor information

Department of Health (UK)
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website http://www.doh.gov.uk

Funders

Funder type

Government

Queen's Medical Centre University Hospital NHS Trust (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/08/2007 Yes No