The effect of intraoperative fluid status optimisation guided by oesophageal doppler monitoring on outcome of patients following urgent or emergency laparotomy

ISRCTN ISRCTN11799696
DOI https://doi.org/10.1186/ISRCTN11799696
Secondary identifying numbers G0100043
Submission date
18/05/2001
Registration date
18/05/2001
Last edited
16/11/2011
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr John Kinsella
Scientific

Department of Anaesthesia
Glasgow Royal Infirmary
University of Glasgow
8-16 Alexandra Parade
Glasgow
G4 0SF
United Kingdom

Phone +44 (0)141 211 4625
Email j.kinsella@clinmed.gla.ac.uk

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Hospital
Study typeNot Specified
Scientific title
Study acronymFLOES
Study objectivesNot provided at time of registration
Ethics approval(s)Not provided at time of registration
Health condition(s) or problem(s) studiedFluid status in emergency laparotomy
InterventionIn the intervention group pulse pressure variation measurements were used to guide fluid boluses of 6% Hydroxyethylstarch 130/0.4
Intervention typeOther
Primary outcome measureSerum urea, creatinine and cystatin C levels were measured prior to and at the end of surgery and postoperatively on day 1, day 3 and day 5.
Secondary outcome measuresNot provided at time of registration.
Overall study start date01/05/1999
Completion date01/05/2002

Eligibility

Participant type(s)Patient
Age groupAdult
SexNot Specified
Target number of participants30
Key inclusion criteriaNot provided at time of registration.
Key exclusion criteriaNot provided at time of registration.
Date of first enrolment01/05/1999
Date of final enrolment01/05/2002

Locations

Countries of recruitment

  • Scotland
  • United Kingdom

Study participating centre

Department of Anaesthesia
Glasgow
G4 0SF
United Kingdom

Sponsor information

Medical Research Council (MRC) (UK)
Research council

20 Park Crescent
London
W1B 1AL
United Kingdom

Phone +44 (0)20 7636 5422
Email clinical.trial@headoffice.mrc.ac.uk
Website http://www.mrc.ac.uk

Funders

Funder type

Government

Medical Research Council (MRC) (UK)
Government organisation / National government
Alternative name(s)
Medical Research Council (United Kingdom), UK Medical Research Council, MRC
Location
United Kingdom

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/06/2008 Yes No