Contact information
Type
Scientific
Primary contact
Dr Lukas Zahner
ORCID ID
Contact details
Institute for Exercise and Health Sciences
University of Basle
Brüglingen 33
Basel
4052
Switzerland
+41 (0)61 377 87 55
lukas.zahner@unibas.ch
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
SWI05-013 (KISS)
Study information
Scientific title
Acronym
KISS
Study hypothesis
It is hypothesised that the intervention will result in an increase of physical activity, fitness and health in the intervention group compared to the controls.
Ethics approval
Approved by the Ethics Committees of the University of Basel, the University of Zürich, as well as by the Cantonal Ethical Committee of Aargau, Switzerland.
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Other
Trial type
Quality of life
Patient information sheet
Condition
Healthy children with about 20% obese children included
Intervention
The intervention will comprise environmental changes at school (i.e. daily physical activity) and individual components at home aiming at improving pattern and extent of physical activity and the control will have a usual school physical activity curriculum.
Intervention type
Other
Phase
Not Applicable
Drug names
Primary outcome measures
1. Total physical activity
2. Aerobic fitness
3. Percentage body fat
4. Bone mineral density of the femur
5. Quality of life
Secondary outcome measures
1. Body composition (total lean and fat mass)
2. Body fat distribution
3. Additional cardiovascular risk factors
4. Bone mineral density of total body and lumbar spine and as well as bone mineral content of all measured sites
5. Bone metabolism
6. Overall fitness
7. Psychosocial health, social coping, stress coping, social anxiety, self esteem and addiction
8. Nutritional behaviour
Overall trial start date
31/10/2005
Overall trial end date
31/12/2009
Reason abandoned
Eligibility
Participant inclusion criteria
Healthy children
Participant type
Patient
Age group
Child
Gender
Both
Target number of participants
600
Participant exclusion criteria
Children with severe chronic disease (cyanotic heart disease, cystic fibrosis, asthma, motor disabilities)
Recruitment start date
31/10/2005
Recruitment end date
31/12/2009
Locations
Countries of recruitment
Switzerland
Trial participating centre
Institute for Exercise and Health Sciences
Basel
4052
Switzerland
Sponsor information
Organisation
Swiss Federal Institute of Technology and University of Zurich (Switzerland)
Sponsor details
Exercise Physiology
Winterthurstr. 190
Zürich
8057
Switzerland
+41 (0)44 635 50 06
kriemler@access.unizh.ch
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
Federal Office of Sports, Magglingen (Switzerland) (ref: SWI05-013 [KISS])
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
1. 2006 protocol in http://www.ncbi.nlm.nih.gov/pubmed/16756652
2. 2009 crossvalidation of analysis techniques in http://www.ncbi.nlm.nih.gov/pubmed/18285806
3. 2010 results in http://www.ncbi.nlm.nih.gov/pubmed/20179126
4. 2014 results in http://www.ncbi.nlm.nih.gov/pubmed/24498404
Publication citations
-
Protocol
Zahner L, Puder JJ, Roth R, Schmid M, Guldimann R, Pühse U, Knöpfli M, Braun-Fahrländer C, Marti B, Kriemler S, A school-based physical activity program to improve health and fitness in children aged 6-13 years ("Kinder-Sportstudie KISS"): study design of a randomized controlled trial [ISRCTN15360785]., BMC Public Health, 2006, 6, 147, doi: 10.1186/1471-2458-6-147.
-
Crossvalidation of analysis techniques
Kriemler S, Puder J, Zahner L, Roth R, Braun-Fahrländer C, Bedogni G, Cross-validation of bioelectrical impedance analysis for the assessment of body composition in a representative sample of 6- to 13-year-old children., Eur J Clin Nutr, 2009, 63, 5, 619-626, doi: 10.1038/ejcn.2008.19.
-
Results
Kriemler S, Zahner L, Schindler C, Meyer U, Hartmann T, Hebestreit H, Brunner-La Rocca HP, van Mechelen W, Puder JJ, Effect of school based physical activity programme (KISS) on fitness and adiposity in primary schoolchildren: cluster randomised controlled trial., BMJ, 2010, 340, c785.
-
Results
Meyer U, Schindler C, Zahner L, Ernst D, Hebestreit H, van Mechelen W, Rocca HP, Probst-Hensch N, Puder JJ, Kriemler S, Long-term effect of a school-based physical activity program (KISS) on fitness and adiposity in children: a cluster-randomized controlled trial., PLoS ONE, 2014, 9, 2, e87929, doi: 10.1371/journal.pone.0087929.