Condition category
Respiratory
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
08/01/2009
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Paul Walker

ORCID ID

Contact details

Chest Unit
3rd Floor Clinical Science Building
University Hospital Aintree
Longmoor Lane
Liverpool
L9 7AL
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0025107117

Study information

Scientific title

Acronym

Study hypothesis

Whether intravenous aminophylline provides any benefit to patients with acute exacerbations of COPD.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Respiratory: Chronic obstructive pulmonary disease (COPD)

Intervention

Intravenous aminophylline vs placebo

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/02/2002

Overall trial end date

01/02/2005

Reason abandoned

Eligibility

Participant inclusion criteria

80 adult subjects aged 40-80 years.

Participant type

Patient

Age group

Adult

Gender

Not Specified

Target number of participants

40 controls and 40 COPD patients

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/02/2002

Recruitment end date

01/02/2005

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Chest Unit
Liverpool
L9 7AL
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Government

Funder name

Aintree Hospitals NHS Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2005 results in http://www.ncbi.nlm.nih.gov/pubmed/15939732

Publication citations

  1. Results

    Duffy N, Walker P, Diamantea F, Calverley PM, Davies L, Intravenous aminophylline in patients admitted to hospital with non-acidotic exacerbations of chronic obstructive pulmonary disease: a prospective randomised controlled trial., Thorax, 2005, 60, 9, 713-717, doi: 10.1136/thx.2004.036046.

Additional files

Editorial Notes