Condition category
Respiratory
Date applied
16/01/2009
Date assigned
19/02/2009
Last edited
11/12/2014
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Nicholas Hopkinson

ORCID ID

Contact details

Royal Brompton Hospital
Fulham Road
London
SW3 6NP
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

cro870 protocol version 2

Study information

Scientific title

Effect of singing lessons on breathlessness in patients with chronic obstructive pulmonary disease (COPD): a randomised controlled single-blind trial

Acronym

ESLBPC

Study hypothesis

That a course of singing lessons will improve breathlessness in patients with chronic obstructive pulmonary disease (COPD).

Ethics approval

Brompton, Harefield and National Heart and Lung Institute (NHLI) REC, approved on 11/10/2007 (ref: 07/H0708/90)

Study design

Randomised controlled single-blind trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Chronic obstructive pulmonary disease (COPD)

Intervention

Participants will be randomly allocate to the following two arms:
Intervention group: A 6-week course of singing lessons (1 hour/ lesson) twice weekly
Control group: Standard care only

Intervention type

Other

Phase

Not Applicable

Drug names

Primary outcome measures

Single breath counting and breath hold time.

All primary and secondary outcomes will be assessed at 7 weeks.

Secondary outcome measures

1. Quality of life (QOL): St George's Respiratory Questionnaire (SGRQ), Transition Dyspnoea Index, SF-36® Health Survey
2. Shuttle walking test (SWT)

All primary and secondary outcomes will be assessed at 7 weeks.

Overall trial start date

22/01/2009

Overall trial end date

01/08/2009

Reason abandoned

Eligibility

Participant inclusion criteria

1. Both males and females, no age limits
2. COPD patients able to comply with a course of lessons
3. Medical Research Council (MRC) dyspnoea score >3/5

Participant type

Patient

Age group

Other

Gender

Both

Target number of participants

64

Participant exclusion criteria

Unable to comply with course

Recruitment start date

22/01/2009

Recruitment end date

01/08/2009

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Royal Brompton Hospital
London
SW3 6NP
United Kingdom

Sponsor information

Organisation

Imperial College London (UK)

Sponsor details

c/o Gary Roper
South Kensington Campus
London
SW7 2AZ
United Kingdom

Sponsor type

University/education

Website

http://www3.imperial.ac.uk/

Funders

Funder type

Charity

Funder name

Royal Brompton & Harefield Arts (rb&h Arts), Royal Brompton Hospital (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

1. 2010 conference proceedings: Effect Of Singing Lessons In Patients With COPD A Randomised Controlled Trial. Lord VM, Hume V, Cave P, Flude LJ, Kelly JL, and Hopkinson NS. Am. J. Respir. Crit. Care Med., May 2010; 181: A5134.
2. 2010 results in http://www.ncbi.nlm.nih.gov/pubmed/20682030

Publication citations

  1. Results

    Lord VM, Cave P, Hume VJ, Flude EJ, Evans A, Kelly JL, Polkey MI, Hopkinson NS, Singing teaching as a therapy for chronic respiratory disease--a randomised controlled trial and qualitative evaluation., BMC Pulm Med, 2010, 10, 41, doi: 10.1186/1471-2466-10-41.

Additional files

Editorial Notes