Usefulness of a three-step guideline to reduce length of hospital stay for patients with community-acquired pneumonia: a randomised controlled trial

ISRCTN	ISRCTN17875607
DOI	https://doi.org/10.1186/ISRCTN17875607
Secondary identifying numbers	FIS 040139

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr Jordi Carratala
Scientific

Infectious Disease Service
Hospital Universitari de Bellvitge
Feixa Llarga s/n
L´Hospitalet
Barcelona
08907
Spain

Phone	+34 (0)93 260 76 25
Email	jcarratala@wanadoo.es

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Not specified
Study type	Treatment
Scientific title	Usefulness of a three-step guideline to reduce length of hospital stay for patients with community-acquired pneumonia: a randomised controlled trial
Study objectives	The implementation of a three-step guideline would be effective and safe in reducing length of stay for hospitalized patients with community-acquired pneumonia
Ethics approval(s)	Approved by the Ethics Committee of the University of Bellvitge (Comite Etic d´Investigació de l´Hospital Universitari de Bellvitge), July 2004, reference number: 05/FIS-008
Health condition(s) or problem(s) studied	Community-acquired pneumonia
Intervention	Patients will be randomly assigned to one of two groups: 1. Use of a three-step guideline, including early mobilization, and pre-defined criteria for switch antibiotic therapy and hospital discharge 2. Control group (conventional management)
Intervention type	Other
Primary outcome measure	Length of hospital stay
Secondary outcome measures	1. Time to switch 2. Readmission (<30 days) 3. Overall mortality (<30 days) 4. Satisfaction with care
Overall study start date	24/04/2006
Completion date	31/12/2007

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	Both
Target number of participants	376
Total final enrolment	401
Key inclusion criteria	Immunocompetent adults (aged >18 years) who have received a diagnosis of community-acquired pneumonia in the emergency department and are admitted to the hospital
Key exclusion criteria	1. Severe immunosuppression (neutropenia, transplantation, human immunodeficiency virus [HIV] infection) 2. Imminent death 3. Intensive care unit (ICU) admission 4. Shock 5. Complicated pleural effusion 6. Aspiration pneumonia 7. Social problem (homelessness) 8. Not able to drink and eat 9. Absence of written informed consent
Date of first enrolment	24/04/2006
Date of final enrolment	31/12/2007

Infectious Disease Service

Barcelona
08907
Spain

Spanish National Health Service (Fondo de Investigación Sanitaria)
Government

Sinesio Delgado 4
Madrid
28029
Spain

Government

Investigation of Sanitary Funding (Fondo de Investivación Sanitaria) IDIBELL

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	25/06/2012		Yes	No

06/01/2021: Total final enrolment added.