A collaborative primary care-based approach to managing upper respiratory tract infections as a strategy to reduce antibiotic prescribing

ISRCTN ISRCTN18154381
DOI https://doi.org/10.1186/ISRCTN18154381
Secondary identifying numbers COM/2732/04
Submission date
20/06/2006
Registration date
21/09/2006
Last edited
06/02/2014
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof James McElnay
Scientific

Queen's University Belfast
Medical Biology Centre
97 Lisburn Road
Belfast
BT9 7BL
United Kingdom

Study information

Study designPhase 1 is a cluster randomised control trial. Phase 2 is a qualitative approach including focus groups and semi-structured interviews.
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Other
Study typeOther
Scientific title
Study objectivesCan a collaborative primary care-based approach betwen community pharmacists and general practitioners decrease antibiotic prescribing for Upper Respiratory Tract Infections (URTIs).
Ethics approval(s)Ethical approval was granted 20th July 2005 by the Office for Research Ethics Committee Northern Ireland No 3. REC (reference number: 05/NIR03/154).
Health condition(s) or problem(s) studiedUpper Respiratory Tract Infections
InterventionIntervention community pharmacists will assess patients referred from General Practitioner (GP) practices using the Network Organisation Technology Research Center (CENTOR) algorithm to assist them in making an appropriate treatment choice with a non-prescriptive medicine.

Control pharmacists will provide usual care.
Intervention typeOther
Primary outcome measureThe rate of antibiotic prescribing for URTIs.
Secondary outcome measures1. Comparison of treatment success rates of URTIs between Intervention and Control groups
2. Patient satisfaction with URTI management
3. Economic analysis of the cost of the new pharmacy service
Overall study start date01/03/2005
Completion date28/02/2007

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexBoth
Target number of participantsGeneral Practices: 30; Pharmacies: 90; Patients: 7,500
Key inclusion criteria1. General practices with between 3,000 to 8,000 and over 8,000 patients and complete computerised prescribing
2. Community pharmacists who dispense 80% of issued prescriptions
3. Patients:
a. aged over five years
b. who request an appointment or prescription for an URTI
c. who use one of the participating pharmacies
d. who do not have a history of chronic respiratory or cardiac disease
e. who have not previously consulted with a pharmacist about their current symptoms
Key exclusion criteria1. General Practices with less than 2,500 patients and incomplete computerised prescribing
2. Community pharmacists who dispense less than 80% of issued prescriptions
3. Patients:
a. aged under 5 years
b. who do not use one of the participating pharmacies
c. who have a history of chronic respiratory or cardiac disease
d. who have previously consulted with a pharmacist about their current symptoms
Date of first enrolment01/03/2005
Date of final enrolment28/02/2007

Locations

Countries of recruitment

  • Northern Ireland
  • United Kingdom

Study participating centre

Queen's University Belfast
Belfast
BT9 7BL
United Kingdom

Sponsor information

Queen's University Belfast (UK)
University/education

Lanyon Building
University Road
Belfast
BT9 7BL
Northern Ireland
United Kingdom

Phone +44 (0)28 9097 5800
Email g.mcaleavey@qub.ac.uk
ROR logo "ROR" https://ror.org/00hswnk62

Funders

Funder type

Government

Research and Development Office, National Institutes of Health Stroke Scale (NIHSS) Central Services Agency (ref: COM/2732/04)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan