Contact information
Type
Scientific
Primary contact
Dr PJ Goadsby
ORCID ID
Contact details
Headache and Migraine Group
Institute of Neurology
Queen Square
London
WC1N 3BG
United Kingdom
+44 020 7829 8749
peterg@ion.ucl.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0263104924
Study information
Scientific title
Acronym
Study hypothesis
A comparative study of the efficacy and safety of intranasal ketamine and midazolam for the acute treatment of migraine with prolonged aura and familial hemiplegic migraine.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Migraine
Intervention
Clinical trial:
1. Intranasal ketamine
2. Midazolam
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measures
Patient diary-based observations of progression of aura
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/09/2001
Overall trial end date
01/12/2005
Reason abandoned
Eligibility
Participant inclusion criteria
30 Patients from Neurology.
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
30
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/09/2001
Recruitment end date
01/12/2005
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Headache and Migraine Group
London
WC1N 3BG
United Kingdom
Sponsor information
Organisation
Department of Health (UK)
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
University College London Hospitals NHS Trust (NHS R&D Support Funding)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2013 results in: http://www.ncbi.nlm.nih.gov/pubmed/23365053
Publication citations
-
Results
Afridi SK, Giffin NJ, Kaube H, Goadsby PJ, A randomized controlled trial of intranasal ketamine in migraine with prolonged aura., Neurology, 2013, 80, 7, 642-647, doi: 10.1212/WNL.0b013e3182824e66.