Contact information
Type
Scientific
Primary contact
Dr MS Marber
ORCID ID
Contact details
Dept of Cardiology
The Rayne Institute
St Thomas' Hospital
Lambeth Palace Road
London
SE1 7EH
United Kingdom
+44 (0)20 7836 5454
mike.marber@kcl.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
PG/97051
Study information
Scientific title
Acronym
Study hypothesis
Effect on ventricular modelling of angioplasty and stenting of the occluded infarct related artery (IRA) among patients with their first Q wave anterior myocardial infarction.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Cardiovascular disease
Intervention
Angiography and angioplasty carried out within 28 days of the acute event. Patients to be randomised into intervention or non-intervention groups.
Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded.
Remaining patients with TIMI grade 0 or I will be randomised to intervention plus optimal medical therapy or optimal medical therapy alone.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/03/1997
Overall trial end date
01/06/1999
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Patients with Thrombolysis in Myocardial Infarction (TIMI) grade 0 or I.
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded.
Recruitment start date
01/03/1997
Recruitment end date
01/06/1999
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Dept of Cardiology
London
SE1 7EH
United Kingdom
Sponsor information
Organisation
British Heart Foundation (UK)
Sponsor details
14 Fitzhardinge Street
London
W1H 6DH
United Kingdom
+44 (0)20 7935 0185
research@bhf.org.uk
Sponsor type
Charity
Website
Funders
Funder type
Charity
Funder name
British Heart Foundation (UK) (ref: PG/97051)
Alternative name(s)
BHF
Funding Body Type
private sector organisation
Funding Body Subtype
Trusts, charities, foundations (both publically funded and privately funded)
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
Results in http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12225709
Publication citations
-
Results
Yousef ZR, Redwood SR, Bucknall CA, Sulke AN, Marber MS, Late intervention after anterior myocardial infarction: effects on left ventricular size, function, quality of life, and exercise tolerance: results of the Open Artery Trial (TOAT Study)., J. Am. Coll. Cardiol., 2002, 40, 5, 869-876.