Condition category
Circulatory System
Date applied
31/10/2001
Date assigned
31/10/2001
Last edited
02/10/2007
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr MS Marber

ORCID ID

Contact details

Dept of Cardiology
The Rayne Institute
St Thomas' Hospital
Lambeth Palace Road
London
SE1 7EH
United Kingdom
+44 (0)20 7836 5454
mike.marber@kcl.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

PG/97051

Study information

Scientific title

Acronym

Study hypothesis

Effect on ventricular modelling of angioplasty and stenting of the occluded infarct related artery (IRA) among patients with their first Q wave anterior myocardial infarction.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Cardiovascular disease

Intervention

Angiography and angioplasty carried out within 28 days of the acute event. Patients to be randomised into intervention or non-intervention groups.
Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded.
Remaining patients with TIMI grade 0 or I will be randomised to intervention plus optimal medical therapy or optimal medical therapy alone.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/03/1997

Overall trial end date

01/06/1999

Reason abandoned

Eligibility

Participant inclusion criteria

Patients with Thrombolysis in Myocardial Infarction (TIMI) grade 0 or I.

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

Not provided at time of registration

Participant exclusion criteria

Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded.

Recruitment start date

01/03/1997

Recruitment end date

01/06/1999

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Dept of Cardiology
London
SE1 7EH
United Kingdom

Sponsor information

Organisation

British Heart Foundation (UK)

Sponsor details

14 Fitzhardinge Street
London
W1H 6DH
United Kingdom
+44 (0)20 7935 0185
research@bhf.org.uk

Sponsor type

Charity

Website

http://www.bhf.org.uk/

Funders

Funder type

Charity

Funder name

British Heart Foundation (UK) (ref: PG/97051)

Alternative name(s)

BHF

Funding Body Type

private sector organisation

Funding Body Subtype

foundation

Location

United Kingdom

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Results in http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12225709

Publication citations

  1. Results

    Yousef ZR, Redwood SR, Bucknall CA, Sulke AN, Marber MS, Late intervention after anterior myocardial infarction: effects on left ventricular size, function, quality of life, and exercise tolerance: results of the Open Artery Trial (TOAT Study)., J. Am. Coll. Cardiol., 2002, 40, 5, 869-876.

Additional files

Editorial Notes