Condition category
Mental and Behavioural Disorders
Date applied
Date assigned
Last edited
Prospectively registered
Overall trial status
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information



Primary contact

Prof Christopher Butler


Contact details

Department of General Practice
Cardiff University
Centre for Health Sciences Research
School of Medicine
3rd Floor
Neuadd Merionnydd
Heath Park
CF14 4XN
United Kingdom

Additional identifiers

EudraCT number number

Protocol/serial number


Study information

Scientific title

Preventing disease through opportunistic, Rapid EngagEMent by Primary care Teams using behaviour change counselling



Study hypothesis

There are three main aims:
1. To determine whether exposing clinicians to blended learning of Behaviour Change Counselling (BCC) leads to patients making more positive changes regarding smoking, risky drinking, physical activity and unhealthy eating, and at what cost?
2. To examine if patients consulting with clinicians exposed to blended learning of Behaviour Change Counselling recall behavioural interventions more often and find them more acceptable and do they state that they intend to change more often?
3. To explore if clinicians exposed to blended learning of BCC feel more efficacious in advising on behaviour change, and committed to behaviour change counselling?

Ethics approval

Multi-centre Research Ethics Committee (MREC) for Wales, 09/05/2007, ref: 07/MRE09/11

Study design

Cluster randomised trial with randomisation at the level of general practice

Primary study design


Secondary study design

Cluster randomised trial

Trial setting

GP practices

Trial type


Patient information sheet

Not available in web format, please use contact details to request a participant information sheet


Behaviour change counselling in patients with unhealthy lifestyles


Clinicians in the experimental group will receive training in Behaviour Change Counselling, using a blended learning, multi-method approach including on-line learning and face to face seminar sessions. Clinicians will then use this when interacting with patients around health behaviour change. The comparison group will provide usual care with the offer of training after the study period.

Intervention type



Drug names

Primary outcome measure

Proportion of patients showing important positive change in one or more of the four behaviours (smoking, alcohol use, exercise and healthy eating) at three months

Secondary outcome measures

Not provided at time of registration

Overall trial start date


Overall trial end date


Reason abandoned (if study stopped)


Participant inclusion criteria

1. Ability to provide informed consent
2. Aged 18 years and over
3. English speaking
4. Screening positive to any of the four behaviours (smoking, alcohol use, exercise and healthy eating)

Participant type


Age group




Target number of participants

24 practices (12 intervention; 12 control)

Participant exclusion criteria

1. Serious acute illness
2. Terminal illness
3. Severe psychiatric illness (as indicated by health professional)

Recruitment start date


Recruitment end date



Countries of recruitment

United Kingdom

Trial participating centre

Cardiff University
CF14 4XN
United Kingdom

Sponsor information


Cardiff University (UK)

Sponsor details

Research and Commercial Division
Cardiff University
30-36 Newport Road
CF24 0DE
United Kingdom

Sponsor type




Funder type


Funder name

National Prevention Research Initiative (NPRI) (UK) (ref: G0501283)

Alternative name(s)

Funding Body Type

Funding Body Subtype


Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Basic results (scientific)

Publication list

2010 protocol in:
2013 results in:
2015 results in:

Publication citations

  1. Protocol

    Spanou C, Simpson SA, Hood K, Edwards A, Cohen D, Rollnick S, Carter B, McCambridge J, Moore L, Randell E, Pickles T, Smith C, Lane C, Wood F, Thornton H, Butler CC, Preventing disease through opportunistic, rapid engagement by primary care teams using behaviour change counselling (PRE-EMPT): protocol for a general practice-based cluster randomised trial., BMC Fam Pract, 2010, 11, 69, doi: 10.1186/1471-2296-11-69.

  2. Results

    Butler CC, Simpson SA, Hood K, Cohen D, Pickles T, Spanou C, McCambridge J, Moore L, Randell E, Alam MF, Kinnersley P, Edwards A, Smith C, Rollnick S, Training practitioners to deliver opportunistic multiple behaviour change counselling in primary care: a cluster randomised trial., BMJ, 2013, 346, f1191.

  3. Results

    Randell E, Pickles T, Simpson SA, Spanou C, McCambridge J, Hood K, Butler CC, Eligibility for interventions, co-occurrence and risk factors for unhealthy behaviours in patients consulting for routine primary care: results from the Pre-Empt study, BMC Fam Pract, 2015 , 16, 133, doi: 10.1186/s12875-015-0359-x.

Additional files

Editorial Notes

22/06/2016: Publication reference added. 15/07/2010: the overall trial end date was changed from 30/11/2009 to 31/12/2010.