Condition category
Musculoskeletal Diseases
Date applied
Date assigned
Last edited
Prospectively registered
Overall trial status
Recruitment status
No longer recruiting
Publication status

Plain English Summary

Not provided at time of registration

Trial website

Contact information



Primary contact

Dr Dawn Carnes


Contact details

Centre for Health Sciences
Queen Mary University of London
2 Newark Street
E1 2AT
United Kingdom

Additional identifiers

EudraCT number number

Protocol/serial number

V10 10.1.11, 69838

Study information

Scientific title

COping with persistent Pain, Effectiveness Research in Self-management



Study hypothesis

Null Hypothesis - There is no difference in pain related disability between those exposed to the self-management chronic pain course and those with usual GP care plus relaxation.

Ethics approval

Cambridgeshire Research Ethics Committee 4, 18/03/2011, ref: 11/EE/0046

Study design

Pragmatic randomised controlled trial

Primary study design


Secondary study design

Randomised controlled trial

Trial setting

GP practices

Trial type


Patient information sheet

Not available in web format, please use contact details to request a participant information sheet


Chronic musculoskeletal pain


1. To test the effectiveness of a self-management course for chronic pain against a control consisting of usual GP care, a patient education leaflet and a relaxation CD.
2. The intervention is a group based, facilitated learning course about coping strategies for living with chronic pain
3. The course is led by a health care professional and a lay person with chronic pain. We aim to have around 12 participants per course
4. The course will cover various aspects of pain education, pain management techniques, posture and movement
5. It will be run over three days within one week with a two hour follow up session after two weeks

Intervention type



Not Applicable

Drug names

Primary outcome measure

Pain-related disability

Secondary outcome measures

1. Health economics: Incremental Cost Utility Ratio (ICUR)
2. Coping skills, anxiety, depression, social integration and self efficacy

Overall trial start date


Overall trial end date


Reason abandoned (if study stopped)


Participant inclusion criteria

Adults (aged 18 or over) with chronic musculoskeletal pain

Participant type


Age group




Target number of participants

700 (703 participants by end of recruitment)

Participant exclusion criteria

1. Not fluent in English
2. Serious active co-morbidity that is more disabling to the individual than chronic pain
3. Serious mental health issues that would make it difficult for an individual to participate in the group course
4. Patients with a life expectancy of less than six months
5. Substance misuse that would make it difficult for an individual to participate in the group course
6. Inability to give informed consent

Recruitment start date


Recruitment end date



Countries of recruitment

United Kingdom

Trial participating centre

Queen Mary University of London
E1 2AT
United Kingdom

Sponsor information


Queen Mary University of London (UK)

Sponsor details

Joint Research and Development Office
Queen Mary Innovation Centre
5 Walden Street
E1 2EF
United Kingdom

Sponsor type




Funder type


Funder name

National Institute for Health Research (NIHR) (UK) – Programme Grants for Applied Research (RP-PG-0707-10189)

Alternative name(s)

Funding Body Type

Funding Body Subtype


Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Basic results (scientific)

Publication list

2013 protocol in:
2013 results in:
2013 results in:
2014 statistical analysis plan in:
2016 results in:
2018 cohort analysis results in:

Publication citations

  1. Protocol

    Carnes D, Taylor SJ, Homer K, Eldridge S, Bremner S, Pincus T, Rahman A, Underwood M, Effectiveness and cost-effectiveness of a novel, group self-management course for adults with chronic musculoskeletal pain: study protocol for a multicentre, randomised controlled trial (COPERS)., BMJ Open, 2013, 3, 1, doi: 10.1136/bmjopen-2012-002492.

  2. Results

    Carnes D, Homer K, Underwood M, Pincus T, Rahman A, Taylor SJ, Pain management for chronic musculoskeletal conditions: the development of an evidence-based and theory-informed pain self-management course., BMJ Open, 2013, 3, 11, e003534, doi: 10.1136/bmjopen-2013-003534.

  3. Results

    Mars T, Ellard D, Carnes D, Homer K, Underwood M, Taylor SJ, Fidelity in complex behaviour change interventions: a standardised approach to evaluate intervention integrity., BMJ Open, 2013, 3, 11, e003555, doi: 10.1136/bmjopen-2013-003555.

  4. Statistical analysis plan

    Kahan BC, Diaz-Ordaz K, Homer K, Carnes D, Underwood M, Taylor SJ, Bremner SA, Eldridge S, Coping with persistent pain, effectiveness research into self-management (COPERS): statistical analysis plan for a randomised controlled trial., Trials, 2014, 15, 59, doi: 10.1186/1745-6215-15-59.

  5. Results

    Taylor SJ, Carnes D, Homer K, Kahan BC, Hounsome N, Eldridge S, Spencer A, Pincus T, Rahman A, Underwood M, Novel Three-Day, Community-Based, Nonpharmacological Group Intervention for Chronic Musculoskeletal Pain (COPERS): A Randomised Clinical Trial, PLoS Med, 2016, 13, 6, e1002040, doi: 10.1371/journal.pmed.1002040.

Additional files

Editorial Notes

11/06/2018: Publication reference added. 15/06/2016: Publication reference added.