Long-term vision gain after PhotoDynamic Therapy of Choroidal NeoVascularisations in pediatric and young adult patients
| ISRCTN | ISRCTN24428087 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN24428087 |
| Secondary identifying numbers | PDT/001 |
- Submission date
- 11/04/2007
- Registration date
- 22/06/2007
- Last edited
- 25/10/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Eye Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Andreas Lipski
Scientific
Scientific
University Eye Clinic of Essen
Hufelandstr. 55
Essen
45138
Germany
| andreas.lipski@uni-duisburg-essen.de |
Study information
| Study design | Open-label, uncontrolled, prospective trial. |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Non randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Treatment |
| Scientific title | Long-term vision gain after PhotoDynamic Therapy of Choroidal NeoVascularisations in pediatric and young adult patients |
| Study acronym | PDT in young CNV |
| Study objectives | To test efficacy and safety of Photodynamic Therapy (PDT) in young patients with Choroidal Neovascularisations (CNV). |
| Ethics approval(s) | No ethics board approval was sought because this study is a collection of prospective case experiences during the last eight years. By the time the first patients were treated no approval was gained. |
| Health condition(s) or problem(s) studied | Choroidal neovascularization in younger patients |
| Intervention | Photodynamic therapy with verteporfin (Visudyne). An infusion of verteporfin (for 10 minutes) and laser application to the retina in one study eye (83 seconds) was performed. There was no treatment of the second eye with this method. |
| Intervention type | Other |
| Primary outcome measure | 1. Visual acuity 2. Lesion size Mean follow-up of 34.4 months. |
| Secondary outcome measures | Application number (per year). Mean follow-up of 34.4 months. |
| Overall study start date | 01/08/1999 |
| Completion date | 01/07/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target number of participants | 15 |
| Key inclusion criteria | 1. Patients below age 30 2. Vision-limiting choroidal neovascularisation |
| Key exclusion criteria | Previous (laser) treatment. |
| Date of first enrolment | 01/08/1999 |
| Date of final enrolment | 01/07/2006 |
Locations
Countries of recruitment
- Germany
Study participating centre
University Eye Clinic of Essen
Essen
45138
Germany
45138
Germany
Sponsor information
University Eye Clinic of Essen (Germany)
Hospital/treatment centre
Hospital/treatment centre
Hufelandstr. 55
Essen
D-45138
Germany
| andreas.lipski@uni-duisburg-essen.de | |
| Website | http://www.essen.de/ |
"ROR" |
https://ror.org/02na8dn90 |
Funders
Funder type
Hospital/treatment centre
University Eye Clinic of Essen (Germany)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan | Not provided at time of registration |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | 20/03/2008 | 25/10/2021 | Yes | No |
Editorial Notes
25/10/2021: Publication reference added.
