Comparison between two commercially available embryo culture media
| ISRCTN | ISRCTN24759945 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN24759945 |
| Secondary identifying numbers | N/A |
- Submission date
- 03/02/2009
- Registration date
- 13/03/2009
- Last edited
- 13/03/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Urological and Genital Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Anneli Stavreus-Evers
Scientific
Scientific
Department of Women's and Children's Health
Uppsala University Hospital
Uppsala
751 85
Sweden
Study information
| Study design | Prospective randomised single centre single-blinded (patients only) sibling study |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Participant information sheet | Not available in web format, please use the contact details below to request a patient information sheet |
| Scientific title | A prospective randomised sibling-oocyte study of two sequential media for culturing cleavage stage embryos |
| Study objectives | Commercially available culture media are expected to be equally efficient in fertilisation and culture of early embryos. |
| Ethics approval(s) | Local ethics committee (Örebro läns landsting) (Sweden) gave approval on the 25th March 2003 (ref: 90/03) |
| Health condition(s) or problem(s) studied | Infertility |
| Intervention | The study included two commercially available sequential media for fertilisation and culture of oocytes. One of the media system was standard in our clinic, while the other media system was standard in the private clinic in our town. It was not expected that there would be a difference. |
| Intervention type | Other |
| Primary outcome measure | 1. Fertilisation rate, measured at 1 day 2. Polynuclei rate, measured at 2 days 3. Cleavage rate, measured at 2 days |
| Secondary outcome measures | 1. Positive human chorionic gonadotrophin (hCG) rate, measured at 1 - 2 weeks. 2. Clinical pregnancy rate, measured at 12 weeks 3. Implantation rate, measured at 12 weeks 4. Delivery rate, measured at 9 months |
| Overall study start date | 01/10/2007 |
| Completion date | 31/12/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Target number of participants | 110 patients/1200 oocytes |
| Key inclusion criteria | All oocytes from patients (aged 24 - 40 years, female) undergoing in vitro fertilisation (IVF) treatment |
| Key exclusion criteria | Does not meet inclusion criteria |
| Date of first enrolment | 01/10/2007 |
| Date of final enrolment | 31/12/2007 |
Locations
Countries of recruitment
- Sweden
Study participating centre
Department of Women's and Children's Health
Uppsala
751 85
Sweden
751 85
Sweden
Sponsor information
Uppsala County Council (Uppsala Läns Landsting) (Sweden)
Government
Government
Kvinno och Barndivisionen
Akademiska sjukhuset
Uppsala
751 85
Sweden
| Website | http://www.lul.se/ |
|---|---|
"ROR" |
https://ror.org/01dv86r63 |
Funders
Funder type
Hospital/treatment centre
Uppsala University Hospital (Sweden) - Centre of Reproduction
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
