Condition category
Not Applicable
Date applied
Date assigned
Last edited
Retrospectively registered
Overall trial status
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information



Primary contact

Prof Jeffrey Sachs


Contact details

Low Library
Room 314
535 West 116th St
New York
United States of America
+1 212 854 8704

Additional identifiers

EudraCT number number


Protocol/serial number


Study information

Scientific title

A pair-matched community intervention trial to assess the impact of an integrated health and development intervention on child survival and the Millennium Development Goals (MDG) in 10 sub-Saharan African countries



Study hypothesis

1. After 5 years of operation, villages exposed to the MVP intervention will have a lower rate of under-5 mortality and parallel gains in MDG-related secondary outcomes when compared to similar villages not receiving the intervention.
2. That the coordinated delivery a multi-sector package of health and development interventions implemented through a broad-based local partnership is feasible in a diversity of sub-Saharan African contexts, and;
3. The intervention package can be delivered at a scalable cost of US$40 per person per year in the health sector and US$110 per person per year in total

Ethics approval

Columbia University Institutional Review Board approved on the 30th of January 2005 (ref: AAAA8202). The latest ethical review was approved on the 17th of April 2009.
Approval has also been received from all host-country IRBs

Study design

Pair-matched community intervention trial

Primary study design


Secondary study design

Case-control study

Trial setting


Trial type


Patient information sheet

See for patient information sheets and informed consents.


Child mortality, Millennium Development Goals


The Millennium Villages Project involves the coordinated and simultaneous delivery of a package of proven interventions in health, agriculture, infrastructure and education at a projected annual cost of US$110 per capita.

Intervention type



Not Applicable

Drug names

Primary outcome measure

Under 5 mortality rate, measured at baseline, after 3 years and after 5 years of intervention exposure

Secondary outcome measures

1. Proportion of under 5s who are:
1.1. Stunted (low height for age Z-score)
1.2. Wasted (low weight for height Z-score)
1.3. Underweight (low weight for age Z-score)
2. Duration of breastfeeding
3. Age at introduction of complementary feeding
4. Proportion of under 5’s with diarrhoea in past 2 weeks
5. Proportion of under 5’s with diarrhoea in past 2 weeks who receive ORS
6. Proportion under 1s immunized against measles
7. Proportion of under 5s treated for pneumonia
8. Prevalence of malaria among under 5s
9. Proportion of under 5s with a fever in the past 2 weeks who receive appropriate anti-malarial treatment
10. Proportion of under 5s sleeping under Long lasting insecticide treated bed-nets
11. Proportion of pregnant women who received an HIV test
12. Proportion of newborns receiving a post-natal check in the first week of life
13. Proportion of women who receive at least 4 ante-natal care (ANC) visits
14. Proportion of births attended by skilled health personnel
15. Survival rate to last grade of primary education
16. Asset based wealth index
17. Proportion of households reporting not enough food for 1 of past 12 months
18. Proportion of the population using an improved drinking water source
19. Proportion of the population using an improved sanitation source
Outcomes will be measured at baseline, after 3 years and after 5 years of intervention exposure

Overall trial start date


Overall trial end date


Reason abandoned (if study stopped)


Participant inclusion criteria

Resident in a Millennium Village Cluster and informed consent to undergo periodic assessments. Selection of comparison villages is based on village-level parameters with the potential to influence child mortality and related MDG outcomes including:
1. agro-ecological zone
2. accessibility (distance to tar roads and markets)
3. principal livelihood strategies
4. crop types
5. levels of electrification
6. numbers of clinics and schools
7. presence of other development projects in the area

Participant type


Age group




Target number of participants

6000 households followed at baseline and after 3 and 5 years of intervention exposure

Participant exclusion criteria

Does not meet inclusion criteria

Recruitment start date


Recruitment end date



Countries of recruitment

Ethiopia, Ghana, Kenya, Malawi, Mali, Nigeria, Rwanda, Senegal, Tanzania, Uganda

Trial participating centre

Low Library
New York
United States of America

Sponsor information


United Nations Development Program (UNDP) - Regional Bureau for Africa (RBA)

Sponsor details

One United Nations Plaza
New York
United States of America

Sponsor type




Funder type


Funder name

United Nations Development Program (UNDP) - Regional Bureau for Africa (RBA) (UNDP CU08-8798)

Alternative name(s)

Funding Body Type

Funding Body Subtype


Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Basic results (scientific)

Publication list

Publication citations

Additional files

Editorial Notes