Contact information
Type
Scientific
Primary contact
Dr Esther Hobson
ORCID ID
Contact details
Sheffield Institute for Translational Neuroscience
B12
385A Glossop Road
Sheffield
S10 2HQ
United Kingdom
e.hobson@sheffield.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
17022
Study information
Scientific title
Acronym
Telehealth in Motor Neurone Disease
Study hypothesis
Motor neurone disease is a rare but debilitating neurological condition that causes paralysis of the bodys muscles leading to severe disability and eventually death. Patients often struggle to travel the long distances to specialist clinics to receive the care they require whilst this expert care is often unavailable in the community. Telehealth has the potential to enable a specialist team to monitor the health and wellbeing of patients and their carers whilst they are at home. This could improve the patient's health, improve the quality of life of both patients and their carers, and lead to more effective use of health resources.
This is a randomised controlled pilot study that will involve 40 patients who are cared for by the Sheffield Motor Neurone Disease care centre and their main informal carer. Half of the participants will use the telehealth system for a minimum of six months and maximum of eighteen months and information will be collected from patients, carers and their care team. This will include collecting clinical outcome measures, health resource use and the opinions and experience of using the system. All participants will continue to receive their usual care.
This is a pilot study. It aims to determine the feasibility and acceptability of the telehealth system to patients, carers and their health care providers. It also aims to determine how a larger trial could successfully evaluate the clinical and cost-effectiveness of the system.
Ethics approval
14/yh/1068; First MREC approval date 15/07/2014
Study design
Randomised; Interventional; Design type: Diagnosis, Process of Care, Treatment
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Condition
Topic: Dementias and neurodegeneration; Subtopic: Motor neurone disease; Disease: Motor neurone disease
Intervention
TiM telehealth system, The TiM telehealth system is a system through which patients and their carers can enter data about their conditon on a weekly basis. Their answers are automatically analysed and are available to their MND team. The team are automatically alerted to a change in their conditon. The system involves using an Android app on a tablet computer. This relays data via 3G mobile signal to the internet and stored on a server after analysis. The tablet computer also provides education and feedback.; Follow Up Length: 18 month(s)
Intervention type
Other
Phase
Not Applicable
Drug names
Primary outcome measures
Feasibility and acceptability; Timepoint(s): End of the trial
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/09/2014
Overall trial end date
01/03/2016
Reason abandoned
Eligibility
Participant inclusion criteria
1. Patients aged 18 years or over with ElEscorial clinically definite or clinically probable categories of MND who have attended the MND clinic at the Royal Hallamshire Hospital, Sheffield
2. Live within 120 minute drive from Sheffield
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
Planned Sample Size: 80; UK Sample Size: 80
Participant exclusion criteria
The main circumstances where patients or carers will be excluded are those in which individuals would be unable to use the telehealth system or give informed consent.
1. Patients attend another MND care centre in the UK.
2. Significant impairment in decision making capacity preventing informed consent by the subject due to a major mental disorder including frontotemporal dementia.
3. Patient unable to use the system due to physical, intellectual or language difficulties and unwilling to permit carer to operate it on their behalf
4. The patient has no eligible informal carer willing to participate in the trial
5. No available mobile or landline telephone or 3G mobile phone reception at the patients home (this is required to use the TiM system)
6. Any other major impairment that may affect their ability to participate in the study
Recruitment start date
01/09/2014
Recruitment end date
01/03/2016
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Sheffield Institute for Translational Neuroscience
Sheffield
S10 2HQ
United Kingdom
Funders
Funder type
Charity
Funder name
Motor Neurone Disease Association (MNDA) (UK)
Alternative name(s)
MNDA
Funding Body Type
private sector organisation
Funding Body Subtype
professional associations and societies
Location
United Kingdom
Funder name
National Institute for Health Research (UK); Grant Codes: Research contract
Alternative name(s)
NIHR
Funding Body Type
government organisation
Funding Body Subtype
Federal/National Government
Location
United Kingdom
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary