Condition category
Mental and Behavioural Disorders
Date applied
28/09/2007
Date assigned
28/09/2007
Last edited
14/10/2014
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof - -

ORCID ID

Contact details

Institute of Nuclear Medicine
University College Hospital
5th Floor
235 Euston Road
London
NW1 2BU
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0263181140

Study information

Scientific title

Acronym

Study hypothesis

Are the transient psychotic like effects induced by delta-9-tetrahydrocannibinol correlated with excess dopamine release in the striatum as measures by (123I)-IBZM single photon emission tomography (SPET)?

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Treatment

Patient information sheet

Condition

Mental and Behavioural Disorders: Psychosis

Intervention

1. THC drug
2. Placebo

Intervention type

Drug

Phase

Not Applicable

Drug names

Cannabis

Primary outcome measures

1. The percentage decrease in specific (123I)-IBZM binding under THC vs placebo conditions
2. The relationship between THC induced PANSS increases and (123I)-IBZM displacement

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/06/2006

Overall trial end date

01/12/2007

Reason abandoned

Eligibility

Participant inclusion criteria

External patients

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

Not provided at time of registration

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/06/2006

Recruitment end date

01/12/2007

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Institute of Nuclear Medicine
London
NW1 2BU
United Kingdom

Sponsor information

Organisation

Record Provided by the NHSTCT Register - 2007 Update - Department of Health

Sponsor details

The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)20 7307 2622
dhmail@doh.gsi.org.uk

Sponsor type

Government

Website

http://www.dh.gov.uk/Home/fs/en

Funders

Funder type

Government

Funder name

University College London Hospitals NHS Foundation Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Funder name

NHS R&D Support Funding (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes