Rehabilitation after myocardial infarction: multicentre randomised controlled trial

ISRCTN	ISRCTN27265832
DOI	https://doi.org/10.1186/ISRCTN27265832
Secondary identifying numbers	RM19

Submission date: 23/01/2004
Registration date: 23/01/2004
Last edited: 25/07/2011

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Robert West
Scientific

University of Wales College of Medicine
Department of Cardiology
WHRI Building
Heath Park
Cardiff
C4 4 XN
United Kingdom

Phone	+44 (0)1222 747747

Study information

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Not Specified
Scientific title
Study objectives	There is little evidence for effectiveness of cardiac rehabilitation following acute myocardial infarction as currently provided in the NHS and in the context of modern therapeutic practice. There are few recent trials and historic trials may be of little relevance, since treatments in cardiac care units, with thrombolysis, aspirin, ß blocker, ACE inhibitor and statins have changed greatly in the past thirty years. The principal objective was to determine the effectiveness of programmes of cardiac rehabilitation, as currently provided and in the current clinical context. The trial aimed to measure the effect of rehabilitation on mortality, morbidity and quality of life of patients following myocardial infarction. Further aims included identification of programmes that are more or less effective and of characteristics of patients who benefit more or less from cardiac rehabilitation and to estimate costs of cardiac rehabilitation.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Cardiovascular diseases: Heart disease
Intervention	1. Comprehensive cardiac rehabilitation 2. Standard care
Intervention type	Other
Primary outcome measure	Outcomes at one year included mortality, morbidity, cardiac medication, health service use, psychological wellbeing and quality of life on standard scales, cardiac risk factors, including smoking, drinking, diet and leisure time activity.
Secondary outcome measures	Not provided at time of registration
Overall study start date	01/04/1996
Completion date	01/04/2000

Eligibility

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target number of participants	Not provided at time of registration
Key inclusion criteria	Not provided at time of registration
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/04/1996
Date of final enrolment	01/04/2000

Locations

Countries of recruitment

United Kingdom

Study participating centre

University of Wales College of Medicine

Cardiff
C4 4 XN
United Kingdom

Sponsor information

Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK)
Government

The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website	http://www.doh.gov.uk

Funders

Funder type

Government

NHS Cardiovascular Disease and Stroke National Research and Development Programme (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	14/12/1996		Yes	No