Condition category
Mental and Behavioural Disorders
Date applied
12/10/2006
Date assigned
12/10/2006
Last edited
28/07/2014
Prospective/Retrospective
Prospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr E Dozeman

ORCID ID

Contact details

EMGO-Institute/VU medical centre
Department of General Practice
Antwoordnummer 2941
Amsterdam
1000 SN
Netherlands
+31 (0)20 4449678
els.dozeman@vumc.nl

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

DIP

Study hypothesis

An indicated, stepped care prevention programme is feasible in homes for the elderly in Amsterdam and reduces the incidence of major disorders of depression and anxiety with 15% compared to care as usual. Total costs of health care use will be lower in the intervention group as compared to ‘care as usual’.

Ethics approval

Ethics approval received from the local medical ethics committee

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Other

Trial type

Prevention

Patient information sheet

Condition

Depressive disorders, Anxiety disorders

Intervention

A stepped care programme consisting watchful waiting, biblio-therapy, life review/Problem Solving Treatment (PST) and consultation of a mental health specialist as compared to usual care.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Incidence of depressive and/or anxiety disorders in residents after one year as compared to usual care.

Secondary outcome measures

1. Symptoms of depression and/or anxiety
2. Psychological measures such as life satisfaction and wellbeing
3. Satisfaction with care and treatment costs

Overall trial start date

01/11/2006

Overall trial end date

01/11/2010

Reason abandoned

Eligibility

Participant inclusion criteria

1. Residents of homes for the elderly in Amsterdam
2. Aged 75 year and older
3. Scoring for symptoms of depression and anxiety on the screening measurement (Center for Epidemiologic Studies Depression scale [CES-D])
4. Capable of informed consent
5. Sufficient understanding of the Dutch language

Participant type

Patient

Age group

Senior

Gender

Both

Target number of participants

180

Participant exclusion criteria

1. Residents meeting criteria for major depression and/or clinical anxiety according to the Mini-International Neuropsychiatric Interview (MINI)
2. Residents suffering cognitive impairment according to the Mini Mental State Examination (MMSE) are also excluded

Recruitment start date

01/11/2006

Recruitment end date

01/11/2010

Locations

Countries of recruitment

Netherlands

Trial participating centre

EMGO-Institute/VU medical centre
Amsterdam
1000 SN
Netherlands

Sponsor information

Organisation

VU University Medical Center/EMGO-Institute (The Netherlands)

Sponsor details

Van der Boechorststraat 7
Amsterdam
1081 BT
Netherlands
+31 (0)20 4448180
emgo@vumc.nl

Sponsor type

Hospital/treatment centre

Website

Funders

Funder type

Research organisation

Funder name

Netherlands Organisation for Health Research and Development (ZonMw) (The Netherlands)

Alternative name(s)

Netherlands Organisation for Health Research and Development

Funding Body Type

private sector organisation

Funding Body Subtype

other non-profit

Location

Netherlands

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2007 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/17346333
2014 cost-effectiveness results in: http://www.ncbi.nlm.nih.gov/pubmed/23765874
2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/23737075

Publication citations

  1. Protocol

    Dozeman E, van Schaik DJ, Beekman AT, Stalman WA, Bosmans JE, van Marwijk HW, Depression and anxiety, an indicated prevention (DIP) protocol in homes for the elderly: feasibility and (cost) effectiveness of a stepped care programme., BMC Geriatr, 2007, 7, 6, doi: 10.1186/1471-2318-7-6.

  2. Results

    van Schaik DJ, Dozeman E, van Marwijk HW, Stek ML, Smit F, Beekman AT, van der Horst HE, Preventing depression in homes for older adults: are effects sustained over 2 years?, Int J Geriatr Psychiatry, 2014, 29, 2, 191-197, doi: 10.1002/gps.3989.

  3. Bosmans JE, Dozeman E, van Marwijk HW, van Schaik DJ, Stek ML, Beekman AT, van der Horst HE, Cost-effectiveness of a stepped care programme to prevent depression and anxiety in residents in homes for the older people: a randomised controlled trial., Int J Geriatr Psychiatry, 2014, 29, 2, 182-190, doi: 10.1002/gps.3987.

Additional files

Editorial Notes