Condition category
Circulatory System
Date applied
09/03/2007
Date assigned
04/05/2007
Last edited
09/03/2010
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Ms Cheryl Carling

ORCID ID

Contact details

PO box 7004
St Olavs Plass
Oslo
N-0130
Norway
+47 98627327
cheryl.carling@kunnskapssenteret.no

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N/A

Study information

Scientific title

Acronym

HIPPO (Health Information Project, Presentation Online)

Study hypothesis

Our two main comparisons were formulated as the following null-hypotheses:
1. The congruence between participants’ values and their treatment decision is not better for positively framed messages showing gain over 10 years than for negatively framed messages showing loss over 10 years.
2. The congruence between participants’ values and their treatment decision is not better for negatively framed messages showing loss over 10 years than for negatively framed messages showing loss per year over 10 years.

Ethics approval

The University at Buffalo (New York, USA), Health Sciences Institutional Review Board, approved on 15 May 2002.

Study design

Randomized controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Hypertension (hypothetical scenario)

Intervention

Presentation of three statements about the effects of antihypertensives in preventing coronary vascular disease over ten years that are framed differently.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Hypothetical treatment decision: to take or not to take antihypertensives.

Secondary outcome measures

No secondary outcome measures

Overall trial start date

01/11/2004

Overall trial end date

31/05/2005

Reason abandoned

Eligibility

Participant inclusion criteria

At least 18 years of age and fluent in Norwegian.

Participant type

Patient

Age group

Adult

Gender

Not Specified

Target number of participants

2400

Participant exclusion criteria

Previous participation in this trial.

Recruitment start date

01/11/2004

Recruitment end date

31/05/2005

Locations

Countries of recruitment

Norway

Trial participating centre

PO box 7004
Oslo
N-0130
Norway

Sponsor information

Organisation

Norwegian Knowledge Centre for the Health Services (Norway)

Sponsor details

PO box 7004
St Olavs Plass
Oslo
N-0130
Norway
+47 23 25 50 00
post@kunnskapssenteret.no

Sponsor type

Other

Website

http://www.kunnskapssenteret.no/

Funders

Funder type

Research council

Funder name

Norwegian research council (Norway)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2010 results in http://www.ncbi.nlm.nih.gov/pubmed/20209127

Publication citations

  1. Results

    Carling CL, Kristoffersen DT, Oxman AD, Flottorp S, Fretheim A, Schünemann HJ, Akl EA, Herrin J, MacKenzie TD, Montori VM, The effect of how outcomes are framed on decisions about whether to take antihypertensive medication: a randomized trial., PLoS ONE, 2010, 5, 3, e9469, doi: 10.1371/journal.pone.0009469.

Additional files

Editorial Notes