INcidence of VENous Thromboembolism after acute stroke in China
| ISRCTN | ISRCTN34425939 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN34425939 |
| Protocol serial number | INVENT-10 |
| Sponsor | Beijing Tiantan Hospital (China) |
| Funders | Glaxosmithkline (China), Beijing Municiple Science and Technology Commission (China) |
- Submission date
- 28/04/2007
- Registration date
- 06/06/2007
- Last edited
- 19/10/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Wang Yongjun
Scientific
Scientific
Tiantan Hospital
Beijing
100050
China
| Phone | +86 (0)10 6701 3383 |
|---|---|
| zhg_doc@yahoo.com |
Study information
| Primary study design | Observational |
|---|---|
| Study design | Multicentre observational, prospective, nested case-control study. |
| Secondary study design | Case-control study |
| Scientific title | INcidence of VENous Thromboembolism after acute stroke in China |
| Study acronym | INVENT-China |
| Study objectives | 1. Incidence of venous thromboembolism after acute stroke in China was lower than in western countries 2. Risk factors are different between Venous Thromboembolism (VTE) and non-VTE 3. Anticoagulation and neurological rehabilation can reduce the incidence |
| Ethics approval(s) | Approval received from the Tiantan Hospital Ethics Committee on the 29th November 2006 (ref: 7). |
| Health condition(s) or problem(s) studied | Venous thromboembolism |
| Intervention | Group A: stroke inpatients with Deep Venous Thrombosis (DVT) during follow up Group B: stroke inpatients without DVT during follow up DVT will be determined by complete-comprehensive ultrasound sonography two weeks (14 ± 3 days) after stroke onset. Possible risk factors will be compared between group A and group B, these will include: 1. stroke subtype 2. NIHSS 3. Medical history 4. Complications 5. High Density Lipoprotein (HDL) 6. Low Density Lipoprotein (LDL) 7. Triglycerides (TG) |
| Intervention type | Other |
| Primary outcome measure(s) |
Incidence of Deep Venous Thrombosis after acute stroke in China, measured at two weeks (14 ± 3 days) after stroke onset. |
| Key secondary outcome measure(s) |
Predict model of VTE in acute stroke in China, measured at two weeks (14 ± 3 days) after stroke onset. |
| Completion date | 08/10/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | |
| Target sample size at registration | 1882 |
| Key inclusion criteria | 1. Older than 18 2. Acute stroke patients within seven days 3. Identified by Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) 4. National Institutes of Health Stroke Scale (NIHSS) item-six more than one |
| Key exclusion criteria | 1. Transient Ischaemic Attacks (TIAs) 2. Sub-Arachnoid Haemorrhage (SAH) 3. Tumour 4. Medical history of VTE |
| Date of first enrolment | 08/05/2007 |
| Date of final enrolment | 08/10/2007 |
Locations
Countries of recruitment
- China
Study participating centre
Tiantan Hospital
Beijing
100050
China
100050
China
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | |
| IPD sharing plan |
Editorial Notes
19/10/2021: Proactive update review. No publications found. Search options exhausted.
