Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0176135497
Study information
Scientific title
Acronym
Study hypothesis
To test if flicker can enhance short-term recall in older people. To test if any flicker effects on short term recall are frequently-specific.
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Other
Patient information sheet
Condition
Signs and Symptoms: Memory
Intervention
Randomised trial. The intervention is learning and recall of words. A flicker machine will occur on light emitting diodes, the randomisation will be the flicker frequencies. It is thought that specific frequencies (near 10Hz) will enhance recognition and lower and higher frequencies will not.
Intervention type
Other
Phase
Not Specified
Drug names
Primary outcome measure
The endpoints of the study will be recognition of words that participants saw during the learning phase. We will test if particular frequencies of flicker that occurred in the learning phase enhance recognition.
Secondary outcome measures
Not provided at time of registration
Overall trial start date
19/12/2003
Overall trial end date
28/02/2005
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
50 healthy people, 50 patients
Participant type
Patient
Age group
Senior
Gender
Both
Target number of participants
100
Participant exclusion criteria
Does not match inclusion criteria
Recruitment start date
19/12/2003
Recruitment end date
28/02/2005
Locations
Countries of recruitment
United Kingdom
Trial participating centre
OPTIMA
Oxford
OX2 6HE
United Kingdom
Sponsor information
Organisation
Department of Health
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
Sponsor type
Government
Website
Funders
Funder type
Hospital/treatment centre
Funder name
Oxford Radcliffe Hospitals NHS Trust (UK)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16515710
Publication citations
-
Results
Williams J, Ramaswamy D, Oulhaj A, 10 Hz flicker improves recognition memory in older people., BMC Neurosci, 2006, 7, 21, doi: 10.1186/1471-2202-7-21.