The correlation of atrial fibrillation and serum electrolyte level changes after coronary artery bypass grafting surgery
| ISRCTN | ISRCTN36486884 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN36486884 |
| Secondary identifying numbers | N/A |
- Submission date
- 24/12/2005
- Registration date
- 05/01/2006
- Last edited
- 25/09/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Edmundas Sirvinskas
Scientific
Scientific
Eiveniu 2
Kaunas
3000
Lithuania
| esirvinskas@yahoo.com |
Study information
| Study design | Randomized placebo-controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | Serum electrolyte level changes can influence the incidence of atrial fibrillation |
| Ethics approval(s) | Approval of Kaunas Region Ethics Committee for Biomedical Research No. 89/2003 |
| Health condition(s) or problem(s) studied | Atrial fibrillation and serum electrolyte balance disorders |
| Intervention | Magnesium sulfate infusion versus normal saline as placebo infusion |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Magnesium sulphate |
| Primary outcome measure | The incidence of atrial fibrillation in both groups |
| Secondary outcome measures | Correlation between serum electrolyte balance and incidence of atrial fibrillation |
| Overall study start date | 01/01/2004 |
| Completion date | 30/05/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Male |
| Target number of participants | 165 patients |
| Key inclusion criteria | 1. Men undergoing elective coronary artery bypass grafting for ischemic heart disease 2. Serum electrolyte leves within normal ranges 3. No diabetes, pulmonary, liver and renal disfunction disease 4. Sinus rhythm before the surgey 5. No atrial fibrillation in the past |
| Key exclusion criteria | 1. Excessive bleeding after the surgery 2. The need of electric heart stimulation after the surgery 3. The need of vasoactive agents after the surgery |
| Date of first enrolment | 01/01/2004 |
| Date of final enrolment | 30/05/2005 |
Locations
Countries of recruitment
- Lithuania
Study participating centre
Eiveniu 2
Kaunas
3000
Lithuania
3000
Lithuania
Sponsor information
Kaunas Medical University, Institute for Biomedical Research (Lithuania)
University/education
University/education
Eiveniu 2
Kaunas
3000
Lithuania
| sirdiskr@kmu.lt | |
"ROR" |
https://ror.org/0069bkg23 |
Funders
Funder type
University/education
Support was provided from departmental sources: Department of Anaesthesiology and Intensive Care, Clinic of Cardiac Surgery, Heart Center, Kaunas Medical University, Lithuania
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
